饲料研究2025，Vol.48Issue(22)：50-55,6.DOI:10.13557/j.cnki.issn1002-2813.2025.22.010
迷迭香酸对颗粒物暴露下肉鸡生长性能、血清抗氧化指标、炎症因子和胃肠道发育的影响
Effects of rosmarinic acid on growth performance,serum antioxidant indexes,inflammatory factors,and gastrointestinal development in broilers exposed to particulate matter
摘要
Abstract
This experiment aimed to investigate the effects of rosmarinic acid on the growth performance,serum antioxidant indexes,inflammatory factors,and gastrointestinal development in broilers exposed to particulate matter(PM).A total of 144 healthy 14-day-old Arbor Acres(AA)broilers were randomly divided into three groups,with six replicates per group and eight broilers per replicate.The control group(group CON)and PM-exposed group(group PM)were fed the basal diet,while the PM-exposed+rosmarinic acid group(group RA)was supplemented with 200 mg/kg rosmarinic acid in the basal diet.The pre-trial period lasted for seven days,and the formal test period lasted for 21 days.The results showed that compared with group CON,the final body weight(FBW),average daily gain(ADG),and average daily feed intake(ADFI)were significantly lower in group PM(P＜0.05),and the feed-to-gain ratio(F/G)was significantly higher(P＜0.05).Compared with group CON,serum glutathione peroxidase(GSH-Px)activity and total antioxidant capacity(T-AOC)were significantly reduced in group PM(P＜0.05),but GSH-Px activity and T-AOC in group RA were significantly higher than in group PM(P＜0.05).Compared with group CON,serum levels of interleukin-1β(IL-1β),interleukin-6(IL-6),interferon-γ(IFN-γ),and tumor necrosis factor-α(TNF-α)were significantly increased in group PM(P＜0.05),whereas IL-1β,IL-6,IFN-γ,and TNF-α levels were significantly lower in group RA than in group PM(P＜0.05).Compared with group CON,the relative weight of the gizzard,jejunum,and ileum was significantly decreased in group PM(P＜0.05).Compared with group PM,the relative weight of the gizzard,proventriculus,jejunum,and ileum was significantly increased in group RA(P＜0.05).The study shows that dietary supplementation with 200 mg/kg rosmarinic acid can effectively alleviate PM-induced inflammatory responses,enhance antioxidant capacity,improve growth performance,and promote the development of the gastrointestinal tract in broilers.关键词
迷迭香酸/颗粒物/肉鸡/炎症/抗氧化能力/生长性能/胃肠道发育Key words
rosmarinic acid/particulate matter/broilers/inflammation/antioxidant capacity/growth performance/gastrointestinal development分类
农业科技引用本文复制引用
周莹,陈京创,王琳燚,孙全友,王改利,席燕燕,李绍钰..迷迭香酸对颗粒物暴露下肉鸡生长性能、血清抗氧化指标、炎症因子和胃肠道发育的影响[J].饲料研究,2025,48(22):50-55,6.基金项目
河南省农业科学院优青项目(项目编号:2024YQ02) （项目编号:2024YQ02）
河南省自然科学基金青年项目(项目编号:242300420494) （项目编号:242300420494）
