生物加工过程2025，Vol.23Issue(6)：597-604,8.DOI:10.3969/j.issn.1672-3678.2025.06.001
低碳非粮碳源微生物升级转化
Microbial upgrading conversion of low-carbon non-food carbon sources
摘要
Abstract
Biological manufacturing is recognized as a crucial pathway for achieving the high-value conversion from low-value carbon sources.However,microbial fermentation-based biological manufacturing is faced with the dilemma of competing for food resources with human due to its reliance on sugar-based carbon material derived from food.Significant efforts have been contributed to the development of novel microbial conversion systems utilizing low-carbon and non-food carbon sources as substrates,which can not only alleviate the heavy reliance of biological manufacturing on food resources but also promote the realization of dual-carbon goals through the use of low-carbon and non-food carbon sources.In this review,we summarized the current approaches of microbial upgrading conversion of low-carbon and non-food carbon sources,and highlighted the key challenges such as disconnection in carbon source conversion,poor microbial tolerance,complex metabolic pathways,and low metabolic efficiency.In the end,we proposed potential strategies based on AI+synthetic biology to advance the technology in this field.关键词
低碳碳源/非粮高聚物碳源/绿色制造/微生物细胞工厂/偶联转化Key words
low-carbon carbon sources/non-food polymeric carbon sources/green manufacturing/microbial cell factories/coupled conversion分类
生物科学引用本文复制引用
战春君,马成伟,曾安平..低碳非粮碳源微生物升级转化[J].生物加工过程,2025,23(6):597-604,8.基金项目
浙江省智能低碳生物合成重点实验室开放课题(2024ZY01025) （2024ZY01025）
浙江省重点实验室开放课题(2024E10053) （2024E10053）
浙江省"尖兵""领雁"科技计划(2025C01094) （2025C01094）
