陕西中医药大学学报2026,Vol.49Issue(1):40-44,5.DOI:10.13424/j.cnki.jsctcm.2026.01.07
揿针联合疏肝调神针法治疗卒中后抑郁疗效观察
Observation of the Efficacy of Acupuncture Combined with Liver Soothing and Mind-Regulating Acupuncture in the Treatment of Post-Stroke Depression
摘要
Abstract
Objective To observe the clinical efficacy of acupuncture combined with liver soothing and regulating acupuncture in the treatment of post-stroke depression.Methods A total of 60 patients with post-stroke depressio were recruited and divided into control group(30 cases)and observation group(30 cases)by random number table method.The patients in both groups were treated with drugs for the primary disease,on this basis,the control group was given oral administration of haloperidol and melitripxin tablets,and the observation group was treated with acupuncture and liver soothing and mental acupuncture,among which acupuncture was used to treat Neiguan,Shenmen,Xinyu,Liver,Spleen and Kidney.The acupuncture method of soothing the liver and regulating the mind is used to treat acupoints from Baihui,Yintang,Hegu,Taichong,Zusanli,Sanyinjiao,Zhongguan,Qihai and Guanyuan.After 4 weeks of treatment,the changes of Hamilton Depression Rating Scale(HAMD-17)score,modified Barthel index(MBI)score,National Institutes of Health Stroke Scale(NIHSS)score,serum brain-derived neurotrophic factor(BDNF)and homocysteine(HCY)levels were observed between the two groups,and the efficacy of the two groups was compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the HAMD-17 score and NIHSS score in both groups were lower than those before treatment(P<0.05),and the MBI score was higher than that before treatment(P<0.05).The serum BDNF level was higher than before treatment(P<0.05),and the HCY level was lower than that before treatment(P<0.05).Conclusion Acupuncture combined with liver soothing and neurotherapy acupuncture has a good effect on patients with PSD,which can regulate the levels of serum BDNF and HCY,improve the depressive symptoms and neurological deficits of patients,and improve the living ability of patients.关键词
揿针/疏肝调神针法/卒中后抑郁/脑源性神经营养因子/同型半胱氨酸Key words
pressing needle/liver soothing and regulating acupuncture/post-stroke depression/brain-derived neurotrophic factor/homocysteine分类
医药卫生引用本文复制引用
雍启正,卢尹凤,樊吟秋,肖洪波,杨骏..揿针联合疏肝调神针法治疗卒中后抑郁疗效观察[J].陕西中医药大学学报,2026,49(1):40-44,5.基金项目
国家自然科学基金项目(82104994) (82104994)
安徽省自然科学基金项目(109066010008) (109066010008)
安徽省临床医学研究转化专项(皖科社秘[2023]310号) (皖科社秘[2023]310号)
安徽省第一批省级区域中医康复中心建设项目(皖中医药服务秘[2022]34号) (皖中医药服务秘[2022]34号)
安徽中医药大学校级自然科学研究项目(2020sfyzc12) (2020sfyzc12)