陕西科技大学学报2026，Vol.44Issue(1)：69-76,8.
不同产地及生长年限黄芪药材活性成分积累分布规律研究
Research on the accumulation and distribution pattern of active ingredients in Astragalus membranaceus from different origins and growth years
摘要
Abstract
Explore the accumulation and distribution patterns of active ingredients in Astraga-lus membranaceus from different origins and growth years,providing a basis for effectively controlling the quality of Astragalus membranaceus.The content of astragaloside Ⅳ was de-termined using HPLC-ELSD,while Calycosin-7-O-β-D-glucoside was determined using HPLC-UVD.Total saponins and total flavonoids were quantified by ultraviolet spectropho-tometry.Among three-year-old Astragalus samples from different origins,Shaanxi exhibited the highest astragaloside Ⅳ content,followed by Inner Mongolia,Shanxi,and Gansu.The Calycosin-7-O-β-D-glucoside content ranked from highest to lowest as Gansu,Inner Mongo-lia,Shaanxi,and Shanxi.For Shaanxi Astragalus of different growth years,three-year-old sam-pies showed the highest astragaloside Ⅳ(0.162％)and total saponin(4.28％)contents,which subsequently declined.The Calycosin-7-O-β-D-glucoside(0.045 2％)and total flavonoid(0.584％)contents peaked in seven-year-old samples.For medicinal use targeting astragaloside Ⅳor total sap-onins,harvesting three-year-old Astragalus is optimal;for Calycosin-7-O-β-D-glucoside or total fla-vonoids,six to seven-year-old Astragalus is preferred.关键词
黄芪/产地/生长年限/黄芪甲苷/毛蕊异黄酮葡萄糖苷/质量标志物Key words
Astragalus membranaceus/origins/growth years/astragaloside Ⅳ/calycosin-7-O-β-D-glucoside/quality markers分类
医药卫生引用本文复制引用
李楠,李莎莎,苏格萍,郭佳琪,周恬甜,屈雯..不同产地及生长年限黄芪药材活性成分积累分布规律研究[J].陕西科技大学学报,2026,44(1):69-76,8.基金项目
陕西省重点研发-重点产业创新链(群)-农业领域科技计划项目(2024NC-ZDCYL-04-14) （群）
陕西省科技厅重点研发-关键核心技术攻关-社会发展领域科技计划项目(2024SF-GJHX-08) （2024SF-GJHX-08）
陕西省西安市未央区科技计划项目(202309) （202309）
桂林医学院广西药物分子发现与成药性优化重点实验室开放基金项目(GKLDDO-2024-03) （GKLDDO-2024-03）
