中国饲料Issue(1)：36-42,7.DOI:10.15906/j.cnki.cn11-2975/s.2024100038-12
诱变对栗褐芽孢杆菌B19代谢物及抗氧化能力的影响
Effect of mutagenesis on the metabolic components and antioxidant capacity of Bacillus subtilis B19 strain
摘要
Abstract
Bacillus badius B19 is a strain with chlorogenic acid synthesis ability.To explore the effect of morphology and metabolites on B ac illus b adius,the morphological characteristics and antioxidant activity of Bacillus badius B19 and its mutant strains UWB19-14 and CA55-1 were determined.The content and composition of metabolites in the strains were analyzed by liquid chromatography-mass spectrometry.The results showed that the average length of the mutagenic strain increased by 103.03%and the antioxidant activity of the mutagenised strain was enhanced.A total of 401 metabolites,mainly amino acids and their derivatives,carbohydrates and organic acids,were identified from Bacillus badius B19 and its mutant strains.Differential metabolite enrichment analysis revealed that the mutagenised differential metabolites were mainly enriched in amino acid biosynthesis pathway,ABC transporter and biosynthesis pathway of secondary metabolites.This study provided a theoretical guidance for the further development and utilization of this strains.关键词
栗褐芽孢杆菌/诱变/代谢组学/抗氧化Key words
Bacillus badius/mutation/metabolomics/antioxidation分类
农业科技引用本文复制引用
唐洁,朱平川,张俊洁,龚彬婷,朱文虎,李向荣,李晨光,樊宪伟..诱变对栗褐芽孢杆菌B19代谢物及抗氧化能力的影响[J].中国饲料,2026,(1):36-42,7.基金项目
广西重点研发项目:天然抑菌剂绿原酸微生物合成关键技术及无抗健康养殖应用示范(桂科AB21238005) （桂科AB21238005）
南宁市"邕江计划"领军人才团队专项(2024017) （2024017）
