中国实用妇科与产科杂志2025，Vol.41Issue(12)：1178-1183,6.DOI:10.19538/j.fk2025120107
生育力保存中控制性卵巢刺激方案的选择
Selection of controlled ovarian stimulation protocols in fertility preservation
摘要
Abstract
Advancements in fertility preservation technologies have enabled patients with oncological and non-oncological diseases but with high risk of decreased fertility to retain their reproductive potential.The optimal selection of controlled ovarian stimulation(COS)protocols is crucial for enhancing the efficiency and safety of fertility preservation.This article systematically reviews the development of COS protocols in fertility preservation,focusing on the specific needs of cancer patients.It analyzes the application value of innovative protocols such as random-start and dual stimulation,and discusses the safety of hormone-protective protocols.Based on the evidence-based medical evidence,an individualized decision-making framework integrating tumor type,ovarian reserve,and treatment window is constructed.Prospects for the application of AI prediction models and stem cell technologies are also explored,aiming to provide an evidence for clinical practice.关键词
生育力保存/控制性卵巢刺激/肿瘤/卵巢功能不全Key words
fertility preservation/controlled ovarian stimulation/neoplasms/ovarian insufficiency分类
医药卫生引用本文复制引用
王萌莹,孙宁霞..生育力保存中控制性卵巢刺激方案的选择[J].中国实用妇科与产科杂志,2025,41(12):1178-1183,6.基金项目
National Key Research and Development Program of China(2022YFA1303900) （2022YFA1303900）
General Project of the National Natural Science Foundation of China(82271662) （82271662）
Guideline Project of the Military Logistics Scientific Research Key Project(BHJ23C011) 国家重点研发计划(2022YFA1303900) （BHJ23C011）
国家自然科学基金面上项目(82271662) （82271662）
军队后勤科研重点项目指南立项(BHJ23C011) （BHJ23C011）
