中国现代医学杂志2026，Vol.36Issue(2)：31-35,5.DOI:10.3969/j.issn.1005-8982.2026.02.005
淋巴细胞相关炎症指数在甲状腺乳头状癌淋巴结转移中的研究进展
Research progress on lymphocyte-related inflammatory indices in lymph node metastasis of papillary thyroid carcinoma
摘要
Abstract
In recent years,the interplay between inflammation and tumors has become a research focus,particularly offering new perspectives for predicting lymph node metastasis(LNM)in patients with papillary thyroid carcinoma(PTC).This review systematically summarized the molecular mechanisms linking neutrophil-to-lymphocyte ratio(NLR),lymphocyte-to-monocyte ratio(LMR),platelet-to-lymphocyte ratio(PLR),and systemic immune-inflammation index(SII)with tumor cells.It revealed that SII accurately reflects the entire tumor immune response by integrating platelet-mediated angiogenesis,neutrophil-driven inflammatory cascades,and dynamic lymphocyte depletion.Moreover,a preoperative decision tree model based on these inflammatory indices improved the positive rate of central lymph node dissection,providing a theoretical basis for precise risk stratification and optimization of individualized treatment strategies for PTC patients with LNM.关键词
甲状腺乳头状癌/中央区淋巴结转移/炎症指标Key words
papillary thyroid carcinoma/central lymph node metastasis/inflammatory indices分类
医药卫生引用本文复制引用
闵楠,胡军,朱武飞..淋巴细胞相关炎症指数在甲状腺乳头状癌淋巴结转移中的研究进展[J].中国现代医学杂志,2026,36(2):31-35,5.基金项目
湖北省自然科学基金指导性项目(No:2023AFC003) （No:2023AFC003）
