中国药理学通报2026，Vol.42Issue(1)：17-21,5.DOI:10.12360/CPB202508037
迷走神经刺激在缺血性脑卒中后神经功能修复中的研究进展
Progress of vagus nerve stimulation in neurological repair after ischemic stroke
摘要
Abstract
Stroke is a leading cause of disability worldwide,with approximately 75%of survivors suffering from long-term neurological dysfunction that severely impacts their quality of life.Studies have found that vagus nerve stimulation(VNS),delivered through either implantation or transcutaneous methods,can improve neurological impairment after a stroke.However,there is currently no systematic review summarizing the research findings in this field.Therefore,this paper reviews the research progress on neurological function recovery in clinical and animal models of ischemic stroke following VNS.It focuses on discuss-ing the therapeutic parameters and potential underlying mecha-nisms.The aim is to comprehensively elucidate the effects of VNS on post-stroke neurological recovery,provide a reference for future research,and promote the clinical application of VNS in the rehabilitation of stroke patients.关键词
脑卒中/迷走神经/迷走神经刺激/康复/神经修复/机制Key words
stroke/vagus nerve/vagus nerve stimulation/reha-bilitation/neurological recovery/mechanisms分类
医药卫生引用本文复制引用
李佩怡,王洪蕴,楚世峰,张钊,陈乃宏..迷走神经刺激在缺血性脑卒中后神经功能修复中的研究进展[J].中国药理学通报,2026,42(1):17-21,5.基金项目
国家自然科学基金资助项目(82374060) （82374060）
中国医学科学院医学与健康科技创新工程(2021-I2M-1-020) （2021-I2M-1-020）
