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细胞重编程技术进展及应用展望

汤琦 夏叶 何斌

中国医学前沿杂志(电子版)2025,Vol.17Issue(11):16-22,7.
中国医学前沿杂志(电子版)2025,Vol.17Issue(11):16-22,7.DOI:10.12037/YXQY.2025.11-03

细胞重编程技术进展及应用展望

Progress and application prospect of cell reprogramming

汤琦 1夏叶 1何斌1

作者信息

  • 1. 上海干细胞临床转化研究院,上海 200120
  • 折叠

摘要

Abstract

Cell reprogramming is a key frontier direction in the field of cell therapy.With the deepening of scientists'understanding in both in ivtro and in vivo reprogramming techniques,many important advances have been made in just over a decade.At present,somatic cell reprogramming technology has really reached a critical stage that can solve the unmet clinical needs and implement industrialization.This paper reviews the reprogramming mechanism and research progress of several mainstream technical paths of somatic cell reprogramming,selects the four most representative application directions from the perspective of actual clinical value,and future prospects on the industrial transformation.

关键词

细胞重编程/转分化/技术路径/进展/应用

Key words

Cell reprogramming/Transdifferentiation/Technical route/Progress/Application

引用本文复制引用

汤琦,夏叶,何斌..细胞重编程技术进展及应用展望[J].中国医学前沿杂志(电子版),2025,17(11):16-22,7.

基金项目

Peak Disciplines(Type Ⅳ)of Institutions of Higher Learning in Shanghai(Stem Cell and Translation) 上海高校Ⅳ类高峰学科建设(干细胞与转化)项目 (Type Ⅳ)

中国医学前沿杂志(电子版)

OA北大核心

1674-7372

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