中外医学研究2026，Vol.24Issue(1)：25-28,4.DOI:10.14033/j.cnki.cfmr.2026.01.007
血清IL-8、LPS表达水平与重症急性胰腺炎患者短期预后的关系
Relationship Between Serum IL-8,LPS Expression Levels and Short-Term Prognosis of Patients with Severe Acute Pancreatitis
成赋斌 1吴文进1
作者信息
- 1. 武警广东总队医院 广东 广州 510507
- 折叠
摘要
Abstract
Objective:To explore the relationship between the expression levels of serum interleukin-8(IL-8)and endotoxin[Lipopolysaccharide(LPS)]and the short-term prognosis of patients with severe acute pancreatitis(SAP),and to provide new reference indicators for the early clinical assessment of patients'conditions and prognosis.Method:120 SAP patients who visited the Hospital of the Guangdong Armed Police Corps from January 2022 to January 2025 were selected as the research subjects.Patients were classified into a favorable prognosis group(n=98)and an unfavorable prognosis group(n=22)based on their short-term prognosis.The expression levels of serum IL-8 and LPS in the two groups were detected,and their correlations with the short-term prognosis of the patients were analyzed.Result:Serum IL-8 and LPS expression levels were higher in the poor prognosis group than in the favorable prognosis group,and the difference was statistically significant(P<0.05).The expression levels of serum IL-8 and LPS are both independent risk factors for the short-term prognosis of SAP patients.ROC curve analysis shows that they have certain predictive value for the short-term prognosis of patients.Conclusion:Serum IL-8 and LPS expression levels are closely associated with the short-term prognosis of SAP patients.The combined detection can provide an important basis for the early assessment of the prognosis of patients and a reference for formulating personalized treatment plans.关键词
重症急性胰腺炎/白细胞介素-8/血清/内毒素/炎症因子Key words
Severe acute pancreatitis/Serum IL-8/Serum/Lipopolysaccharide/Inflammatory factors引用本文复制引用
成赋斌,吴文进..血清IL-8、LPS表达水平与重症急性胰腺炎患者短期预后的关系[J].中外医学研究,2026,24(1):25-28,4.
