北京中医药2025,Vol.44Issue(11):1397-1400,4.DOI:10.16025/j.1674-1307.2025.11.005
儿童特应性皮炎与肠道菌群的相关性探讨及治疗
Correlation between pediatric atopic dermatitis and gut microbiota and its treatment
摘要
Abstract
Pediatric atopic dermatitis(AD)is a common chronic inflammatory skin disease,the pathogenesis of which involves immune imbalance and gut microbiota dysbiosis.The interaction between the heart and kidneys and the mutual coordination of water and fire are core elements in maintaining the body's yin-yang balance.In the state of"disharmony between water and fire",functional dysfunction of the heart,spleen,and kidneys is closely associated with gut microbiota imbalance as well as the onset and progression of pediatric AD.Based on the therapeutic goal of restoring"harmony between water and fire",Professor XU Jia developed Zishui Qingxin Decoction,which achieves multi-organ regulation through"nourishing kidney water,clearing heart fire,and regulating the spleen and stomach".This formula can effectively alleviate clinical symptoms of AD and reduce recurrence frequency,and it is expected to provide a new therapeutic approach for regulating gut microbiota in children with AD.关键词
特应性皮炎/肠道菌群/水火未济/水火既济/滋水清心饮Key words
atopic dermatitis/gut microbiota/disharmony between water and fire/harmony between water and fire/Zishui Qingxin Decoction引用本文复制引用
孙苏洋,徐佳..儿童特应性皮炎与肠道菌群的相关性探讨及治疗[J].北京中医药,2025,44(11):1397-1400,4.基金项目
青年岐黄学者支持项目(国中医药人教发[2020]7号) (国中医药人教发[2020]7号)
北京市中医药科技发展资金项目(BJZYYB-2023-72) (BJZYYB-2023-72)
首都卫生发展科研专项(首发2024-3-7141) (首发2024-3-7141)
首都医科大学附属北京中医医院中医/中西医结合治疗儿童特应性皮炎临床优势病种青年学术沙龙项目(2024-QNXSSL-04) (2024-QNXSSL-04)