磁共振成像2026，Vol.17Issue(1)：134-139,6.DOI:10.12015/issn.1674-8034.2026.01.021
磁共振扩散峰度成像在抑郁症患者脑白质微结构中的研究进展
Research progress of magnetic resonance diffusion kurtosis imaging on the microstructure of white matter in patients with major depressive disorder
买丽 1李孝忠 2伍东洋 1李玉宁1
作者信息
- 1. 甘肃中医药大学第一临床医学院,兰州 730000
- 2. 甘肃中医药大学附属医院放射科,兰州 730000
- 折叠
摘要
Abstract
Depression is a severe mental disorder characterized by persistent low mood,loss of interest and anhedonia,accompanied by abnormal cognitive,behavioral and physiological functions.In severe cases,suicidal thoughts or behaviors may occur.The global prevalence rate is approximately 5%,resulting in a heavy socio-economic burden.Diffusion kurtosis imaging is a non-Gaussian diffusion technique based on water molecules,which can demonstrate the high heterogeneity of water molecule diffusion limitations and better study the white matter properties of complex fibrous regions,thereby obtaining the morphological parameters of nerve fibers.At present,most research on depression focuses on diffusion tensor imaging or brain gray matter,making it difficult to fully summarize the current research progress.This article mainly studies the correlation between the parameter values of diffusion kurtosis imaging and the changes in white matter of the brain and clinical symptoms in depression,and proposes future research directions,aimed at providing imaging evidence for the early diagnosis,disease monitoring and optimization of treatment plans of depression.关键词
抑郁症/扩散峰度成像/磁共振成像/脑白质/脑微观结构Key words
major depressive disorder/diffusion kurtosis imaging/magnetic resonance imaging/white matter/brain microstructure分类
医药卫生引用本文复制引用
买丽,李孝忠,伍东洋,李玉宁..磁共振扩散峰度成像在抑郁症患者脑白质微结构中的研究进展[J].磁共振成像,2026,17(1):134-139,6.
