川北医学院学报2026，Vol.41Issue(1)：100-105,6.DOI:10.3969/j.issn.1005-3697.2026.01.020
女性功能性消化不良伴尿常规异常患者与尿路感染患者的比较研究
Comparative study of female patients with functional dyspepsia accompanied by abnormal urinalysis and female patients with urinary tract infection
摘要
Abstract
Objective:To investigate whether female patients with functional dyspepsia(FD)accompanied by abnormal urinalysis can be distinguished from those with genuine urinary tract infections(UTI),and to compare and analyze potential differences in urinalysis parameters between the two groups while developing a predictive model for differentiation.Methods:This study enrolled 120 female FD patients with abnormal urinalysis and 120 female UTI patients.The Mann-Whitney U test and chi-square test were employed to compare urinalysis parameters and the urinary inflammation index(UII)between the two groups.Receiver operating characteristic(ROC)curve analysis was performed to evaluate the diagnostic efficacy of urinalysis parameters in distinguishing FD from UTIs.Furthermore,Logistic regression analysis was conducted to construct a nomogram-based predictive model.Results:Higher-level of leukocyte esterase(500 Leu/μL),positive urinary protein,occult blood(3+),higher RBCs(≥31/μL),and higher WBCs(≥71/μL)were associated with an odds ratio(OR<1),suggesting a tendency to support UTI(P<0.05).In contrast,lower-level abnormalities in urinalysis parameters were more indicative of FD.The optimal combined predictive model for UTI included occult blood,protein,and leukocyte esterase,achieving an AUC of 0.833(0.778～0.888),with sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),and accuracy of 71.7%,90.8%,88.6%,76.2%,and 81.3%,respectively.Conclusion:Abnormal urinalysis indicators in female FD patients exhibit distinct characteristics from those in UTI.The combination of urinary protein,leukocyte esterase,and occult blood demonstrates superior predictive value for differentiating between these two conditions.These findings provide a valuable foundation for further investigation into the pathogenesis and therapeutic approaches for FD accompanied by abnormal urinalysis indicators.关键词
功能性消化不良/尿路感染/脑-肠-膀胱轴/尿常规Key words
Functional dyspepsia/Urinary tract infection/Brain-gut-bladder-axis/Urinalysis分类
医药卫生引用本文复制引用
廖玉蓉,李溢馨,明文,王茜,贺国斌..女性功能性消化不良伴尿常规异常患者与尿路感染患者的比较研究[J].川北医学院学报,2026,41(1):100-105,6.基金项目
四川省基层卫生事业发展研究中心科研项目(SWFZ23-Y-32) （SWFZ23-Y-32）
