中国妇幼健康研究2026，Vol.37Issue(1)：11-17,7.DOI:10.3969/j.issn.1673-5293.2026.01.002
锰与妊娠期并发症和出生结局的研究进展
Research progress on the associations between manganese exposure and pregnancy complications and birth outcomes
摘要
Abstract
Manganese(Mn),an essential trace element,plays a crucial role in various physiological processes including osteogenesis,carbohydrate and lipid metabolism,antioxidant defense,and neurotransmitter synthesis.Its biological effects are characterized by a dose-dependent biphasic regulatory pattern,which warrants further investigation.With the increasing levels of environmental pollution,population-wide exposure to Mn has risen significantly,particularly affecting pregnant women and fetuses who are considered high-risk groups due to enhanced placental transport capacity and increased physiological requirements during pregnancy.This review summarizes recent research advances on Mn exposure and maternal and child health(MCH)and discusses the complex associations between Mn and pregnancy complications as well as fetal birth outcomes.It aims to provide a comprehensive foundation and conceptual framework for future studies on the impact of Mn exposure on MCH.关键词
锰/暴露/妊娠期并发症/出生结局Key words
manganese/exposure/pregnancy complication/fetal birth outcome分类
医药卫生引用本文复制引用
吴研,王苏苏,冉秀芳,颜崇淮..锰与妊娠期并发症和出生结局的研究进展[J].中国妇幼健康研究,2026,37(1):11-17,7.基金项目
国家重点研发计划项目(2017YFC1600500) （2017YFC1600500）
国家自然科学基金(82304087) （82304087）
