化学试剂2026，Vol.48Issue(1)：36-42,7.DOI:10.13822/j.cnki.hxsj.2025.0214
基于便携式荧光试纸条的水体抗生素比率荧光检测方法研究
Research on a Ratiometric Fluorescence Detection Method for Antibiotics in Water Based on Portable Fluorescent Test Strips
摘要
Abstract
This study aims to develop a novel,highly sensitive and selective method to address the ecological and human health risks posed by antibiotic pollution in aquatic environments.Zeolitic imidazolate framework-8(ZIF-8)was synthesized via a one-step method and systematically characterized using FT-IR,XRD,SEM,TEM,and XPS.A ratiometric fluorescence sensor was then constructed for the detection of levofloxacin(LFX).Under optimal conditions(ZIF-8 concentration:25 μg/mL,pH 7.0,reaction time:5 min),the sensor exhibited a linear detection range of 1～80 μmol/L for LFX,with a detection limit of 0.29 μmol/L.The recovery rate in real water samples was from 98.27％to 101.9％,with RSD≤2.99％,showing good agreement with HPLC results.Additionally,a smartphone-based portable test strip sensor was developed,enabling real-time detection in the range of 10～100μmol/L.This study provides a new approach for designing ZIF-8-based fluorescence sensors and establishes a rapid detection method for trace antibiotic pollutants in environmental water.关键词
ZIF-8/比率型/荧光传感器/左氧氟沙星/荧光试纸Key words
ZIF-8/ratiometric/fluorescence sensor/levofloxacin(LFX)/fluorescent test strip分类
化学化工引用本文复制引用
李凤兰,黄碧妃,林泽彪,黄文杰..基于便携式荧光试纸条的水体抗生素比率荧光检测方法研究[J].化学试剂,2026,48(1):36-42,7.基金项目
福建省自然科学基金项目(2024J08115) （2024J08115）
福建省社会科学基金博士扶持项目(FJ2023BF079). （FJ2023BF079）
