畜牧与饲料科学2025，Vol.46Issue(6)：9-15,7.DOI:10.12160/j.issn.1672-5190.2025.06.002
菜芙蓉黄酮对贵妃鸡免疫功能、血清抗氧化能力及抗病能力的影响
Effects of Abelmoschus manihot(L.)Medic Flavonoids on the Immune Function,Serum Antioxidant Capacity and Disease Resistance of Houdan Chickens
摘要
Abstract
[Objective]This study aimed to investigate the effects of adding different doses of Abelmoschus manihot(L.)Medic flavonoids(AMF)to drinking water on immune organ development,serum immune indices,antioxidant indices,and disease resistance in houdan chickens.[Methods]A total of 120 eight-week-old houdan chickens were randomly divided into five groups.The blank control group(Group C)received normal drinking water;the antibiotic control group(Group A)received water supplemented with 0.005%chlortetracycline;and the low-,medium-,and high-dose AMF groups(Groups L,M,and H)received water supplemented with 0.05%,0.1%,and 0.2%AMF,respectively.After a 42-day feeding trial,immune organ indices,serum immune indices,antioxidant indices,and disease resistance parameters were measured.[Results]Compared with Group C,the thymus index in Groups L and H increased significantly(P<0.05).Serum IgG and IgM levels in Groups A,L,M,and H were significantly higher(P<0.05).Serum IL-6 level was significantly elevated in Group A(P<0.05),while IL-10 level was significantly increased in Group H(P<0.05).Serum SOD content was significantly decreased in Group A(P<0.05)but significantly increased in Group H(P<0.05).Serum CAT content was significantly increased in Groups A,L,M,and H(P<0.05).Serum MDA content was significantly increased in Group A(P<0.05)but significantly decreased in Groups M and H(P<0.05).Serum TP,ALB,and GLO levels in Groups L,M,and H were elevated,though not significantly(P＞0.05).Compared with Group A,the thymus index in Groups L and H increased,while the spleen and bursa indices decreased.All immune organ indices in Group M decreased,though not significantly(P＞0.05).Serum IgM levels in Groups M and H were significantly lower(P<0.05).Serum IL-6 levels in Groups L,M,and H were significantly lower(P<0.05),while IL-10 level was significantly higher in Group H(P<0.05).Serum SOD content in Group H was significantly increased(P<0.05),and MDA content in Groups L,M,and H was significantly decreased(P<0.05).Serum TP,ALB,and GLO levels in Groups L,M,and H were elevated(P＞0.05).[Conclusion]Supplementation of AMF in drinking water can promote immune organ development,increase serum immunoglobulin and anti-inflammatory cytokine levels,enhance antioxidant capacity and disease resistance in houdan chickens,suggesting its potential as an antibiotic alternative.关键词
菜芙蓉黄酮/贵妃鸡/免疫功能/血清抗氧化/抗病能力Key words
Abelmoschus manihot(L.)Medic Flavonoids/houdan chickens/immune function/serum antioxidant capacity/disease resistance分类
农业科技引用本文复制引用
张致行,秦裕亮,莫红芳,许忠裕,奚玉莲,黄杰,蒋玲艳,何东贤,陈孟姣,石宗承,陆星彤,林子睿..菜芙蓉黄酮对贵妃鸡免疫功能、血清抗氧化能力及抗病能力的影响[J].畜牧与饲料科学,2025,46(6):9-15,7.基金项目
2023年广西高校中青年教师科研基础能力提升项目(2023KY1237) （2023KY1237）
2022年广西农业职业技术大学校级课题(YKJ2240) （YKJ2240）
2025年广西农业职业技术大学校级课题(XJG2531) （XJG2531）
中国工程科技发展战略广西研究院咨询研究项目(桂科GXYD24310005) （桂科GXYD24310005）
科技攻关与新产品试制(来科攻220823). （来科攻220823）
