日用化学品科学2026，Vol.49Issue(1)：29-36,8.DOI:10.3969/j.issn.1006-7264.2026.01.005
超声、微电流与红光在护肤品经皮渗透中的对比研究
Comparative study of ultrasound,microcurrent,and red light in the transdermal permeation of skincare products
杨怡文 1黄林冰 2刘洋 3孟德 2唐铁钢 2隆晓菁1
作者信息
- 1. 中国科学院 深圳先进技术研究院,广东 深圳 518055||中科绿谷(深圳)医疗科技有限公司,广东 深圳 518055
- 2. 中科绿谷(深圳)医疗科技有限公司,广东 深圳 518055
- 3. 中国科学院 深圳先进技术研究院,广东 深圳 518055
- 折叠
摘要
Abstract
To assess the effects of non-invasive physical enhancement techniques on the transdermal permeation efficiency of skincare products,a comparative study was conducted on the permeation-enhancing performance of microcurrent,red light,and ultrasound using Sprague-Dawley rats as the experimental model.Multidimensional evaluation—including analysis of local transdermal permeation regions,penetration depth,diffusion area,and absorption quantity—demonstrated distinct enhancement mechanisms among the three modalities.Microcurrent exhibited selective facilitation of active ingredient penetration,while red light induced only a slight increase through follicular bypass pathways,both showing limited overall efficacy.In contrast,ultrasound significantly disrupted the stratum corneum structure through cavitation effects,expanding the local transport area to approximately eight times that of the control group.It markedly outperformed the other techniques in both penetration depth and diffusion range.The findings confirm that ultrasound effectively overcomes the epidermal barrier,achieving at least twice the permeation efficiency for macromolecular components compared with microcurrent and red-light treatments.关键词
超声/微电流/红光/透皮递送Key words
ultrasound/microcurrent/red light/transdermal permeation分类
化学化工引用本文复制引用
杨怡文,黄林冰,刘洋,孟德,唐铁钢,隆晓菁..超声、微电流与红光在护肤品经皮渗透中的对比研究[J].日用化学品科学,2026,49(1):29-36,8.
