青岛大学学报（医学版）2025，Vol.61Issue(6)：835-839,5.DOI:10.11712/jms.2096-5532.2025.61.183
不同年龄组全膝关节置换假体生存率与翻修病因分析
Prosthesis survival rate and causes of revisions after total knee arthroplasty in different age groups
摘要
Abstract
Objective To investigate the differences in prosthesis survival rates and causes of revisions between different age groups after total knee arthroplasty(TKA).Methods A retrospective analysis was performed for the clinical data of 9 341 pa-tients,and according to the age when they underwent TKA for the first time,they were divided into young group(aged ≤45 years),middle-aged group(aged 46-65 years),and elderly group(aged＞65 years).The three groups were compared in terms of the cause of TKA for the first time,long-term prosthesis survival rate,and cause of revision.Results A total of 136 patients underwent revision surgery,with a revision rate of 1.46％.The main causes of revisions were infection(58.82％),prosthetic loose-ning(25.73％),periprosthetic fractures(8.09％),osteolysis(4.41％),and patellofemoral joint problems(2.94％).The etiologi-cal analysis of each age group showed that the young group had a low proportion of patients with knee osteoarthritis(31.82％),while in the middle-aged and elderly groups,the patients with knee osteoarthritis accounted for 95.17％and 97.69％,respectively;there was a significant difference in etiology between the three groups(x2=13.932,P＜0.05).The analysis of prosthesis survival rate in each age group showed that the young group had a lower long-term prosthesis survival rate than the middle-aged and elderly groups(x2=8.180-148.160,P＜0.01).The prosthesis survival rates in the young group at 8,12,and 20 years were 93.18％,90.90％,and 77.27％,respectively,while the 20 year prosthesis survival rate was higher than 98％in the middle-aged and elderly groups.Conclusion For patients aged ≤45 years,non-osteoarthritic causes are the main etiology for primary TKA,with a rela-tively low prosthesis survival rate and revisions mainly due to non-infectious causes;for patients aged＞45 years,knee osteoarthri-tis is the main etiology,and infection is the main cause of revisions.关键词
假体相关感染/关节成形术,置换,膝/再手术/年龄因素Key words
prosthesis-related infections/arthroplasty,replacement,knee/reoperation/age factors分类
医药卫生引用本文复制引用
丁岚峰,李良刚,赵恒心,王远贺,曾国波,田少奇..不同年龄组全膝关节置换假体生存率与翻修病因分析[J].青岛大学学报（医学版）,2025,61(6):835-839,5.基金项目
山东省自然科学基金资助项目(ZR2022MH214) （ZR2022MH214）
吴阶平医学基金会临床科研专项资助基金(320.6750.2024-3-46,320.6750.2024-3-47) （320.6750.2024-3-46,320.6750.2024-3-47）
