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NLRP3 inflammasome activity and pyroptosis are involved in CD206+ macrophage activation by MPO anti-neutrophil cytoplasmic antibodies

Zhaonan Wei Wen Zhang Yongxi Chen Xiaoning An Yinyin Xie Yan Shen Liyan Ni Jing Xu Yimei Wang Pingyan Shen Hao Shi

生物化学与生物物理学报（英文版）2025，Vol.57Issue(11)：1791-1802,12.

生物化学与生物物理学报（英文版）2025，Vol.57Issue(11)：1791-1802,12.DOI:10.3724/abbs.2025080

NLRP3 inflammasome activity and pyroptosis are involved in CD206+ macrophage activation by MPO anti-neutrophil cytoplasmic antibodies

Zhaonan Wei ¹Wen Zhang ¹Yongxi Chen ¹Xiaoning An ²Yinyin Xie ³Yan Shen ⁴Liyan Ni ¹Jing Xu ¹Yimei Wang ¹Pingyan Shen ¹Hao Shi¹

作者信息

1. Department of Nephrology,Shanghai Ruijin Hospital,Shanghai Jiao Tong University,School of Medicine,Shanghai 200025,China||Institute of Nephrology,Shanghai Jiao Tong University,School of Medicine,Shanghai 200025,China
2. Department of Nephrology,Shanghai Ruijin Hospital,Shanghai Jiao Tong University,School of Medicine,Shanghai 200025,China||Institute of Nephrology,Shanghai Jiao Tong University,School of Medicine,Shanghai 200025,China||Department of Nephrology,No. Six People's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200233,China
3. Shanghai Institute of Hematology,State Key Laboratory of Medical Genomics,National Research Center for Translational Medicine at Shanghai,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China
4. Research Center for Experimental Medicine,Ruijin Hospital Affiliated to Shanghai Jiao Tong University,School of Medicine,Shanghai 200025,China
折叠

摘要

关键词

antineutrophil cytoplasmic antibodies/macrophage/NLRP3/pyroptosis/CD206

Key words

antineutrophil cytoplasmic antibodies/macrophage/NLRP3/pyroptosis/CD206

引用本文复制引用

Zhaonan Wei,Wen Zhang,Yongxi Chen,Xiaoning An,Yinyin Xie,Yan Shen,Liyan Ni,Jing Xu,Yimei Wang,Pingyan Shen,Hao Shi..NLRP3 inflammasome activity and pyroptosis are involved in CD206+ macrophage activation by MPO anti-neutrophil cytoplasmic antibodies[J].生物化学与生物物理学报（英文版）,2025,57(11):1791-1802,12.

基金项目

This work was supported by the grants from the National Natural Science Foundation of China(Nos.81470041 and 81000285). （Nos.81470041 and 81000285）

生物化学与生物物理学报（英文版）

ISSN：1672-9145

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