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Increased neutrophil senescence is associated with impaired immunosuppressive activity in systemic lupus erythematosus

Lei Han Xinfang Huang Fengling Huang Qingchen Zhu Huan Wang Tianlin Lu Chunyuan Xiao Jing Xu Xiaoyan Zhang Yichuan Xiao

生物化学与生物物理学报（英文版）2025，Vol.57Issue(11)：1824-1833,10.
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生物化学与生物物理学报（英文版）2025，Vol.57Issue(11)：1824-1833,10.DOI:10.3724/abbs.2025047

Increased neutrophil senescence is associated with impaired immunosuppressive activity in systemic lupus erythematosus

Increased neutrophil senescence is associated with impaired immunosuppressive activity in systemic lupus erythematosus

Lei Han 1Xinfang Huang 1Fengling Huang 2Qingchen Zhu 2Huan Wang 3Tianlin Lu 1Chunyuan Xiao 1Jing Xu 2Xiaoyan Zhang 4Yichuan Xiao2

作者信息

  • 1. Department of Rheumatology,Shanghai East Hospital,Tongji University,School of Medicine,Shanghai 200120,China
  • 2. CAS Key Laboratory of Tissue Microenvironment and Tumor,Shanghai Institute of Nutrition and Health,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China
  • 3. Department of Pharmacy,Hebei Medical University,Shijiazhuang 050011,China
  • 4. Department of Renal and Rheumatology,Xin Hua Hospital Affiliated with Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China
  • 折叠

摘要

关键词

systemic lupus erythematosus/neutrophils/senescence/inhibitory capacity/reactive oxygen species

Key words

systemic lupus erythematosus/neutrophils/senescence/inhibitory capacity/reactive oxygen species

引用本文复制引用

Lei Han,Xinfang Huang,Fengling Huang,Qingchen Zhu,Huan Wang,Tianlin Lu,Chunyuan Xiao,Jing Xu,Xiaoyan Zhang,Yichuan Xiao..Increased neutrophil senescence is associated with impaired immunosuppressive activity in systemic lupus erythematosus[J].生物化学与生物物理学报（英文版）,2025,57(11):1824-1833,10.

基金项目

This work was supported by the grants from the Shanghai Municipal Health Commission(No.202150013)and the National Natural Science Foundation of China(Nos.82201980 and 82271832). （No.202150013）

生物化学与生物物理学报（英文版）

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