生物化学与生物物理学报（英文版）2025，Vol.57Issue(12)：2011-2021,11.DOI:10.3724/abbs.2025116
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs
Hong Huang 1Huifang Tang 2Jian Cui 1Dan Tang 3Xing Xiang 3Jie Mao 4Zhe He 5Hengjing Hu 6Zhangxiu He 7Lu He8
作者信息
- 1. Hunan Provincial Key Laboratory of Multi-omics and Artificial Intelligence of Cardiovascular Diseases,University of South China,Hengyang 421001,China||Clinical Research Center for Myocardial Injury in Hunan Province,Hengyang 421001,China||Institute of Cardiovascular Disease,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China
- 2. Hunan Provincial Key Laboratory of Multi-omics and Artificial Intelligence of Cardiovascular Diseases,University of South China,Hengyang 421001,China||Clinical Research Center for Myocardial Injury in Hunan Province,Hengyang 421001,China||Institute of Cardiovascular Disease,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China||Department of Cardiology,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China
- 3. Hunan Provincial Key Laboratory of Multi-omics and Artificial Intelligence of Cardiovascular Diseases,University of South China,Hengyang 421001,China||Clinical Research Center for Myocardial Injury in Hunan Province,Hengyang 421001,China||Institute of Cardiovascular Disease,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China||Department of Clinical Laboratory Medicine,Institution of Microbiology and Infectious Diseases,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China
- 4. Hunan Provincial Key Laboratory of Multi-omics and Artificial Intelligence of Cardiovascular Diseases,University of South China,Hengyang 421001,China||Clinical Research Center for Myocardial Injury in Hunan Province,Hengyang 421001,China||Institute of Cardiovascular Disease,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China||School of Pharmaceutical Science,Hengyang Medical College,University of South China,Hengyang 421001,China
- 5. Hunan Provincial Key Laboratory of Multi-omics and Artificial Intelligence of Cardiovascular Diseases,University of South China,Hengyang 421001,China||Clinical Research Center for Myocardial Injury in Hunan Province,Hengyang 421001,China||Affiliated Hengyang Hospital of Hunan Normal University&Hengyang Central Hospital,Hengyang 421001,China
- 6. Hunan Provincial Key Laboratory of Multi-omics and Artificial Intelligence of Cardiovascular Diseases,University of South China,Hengyang 421001,China||Clinical Research Center for Myocardial Injury in Hunan Province,Hengyang 421001,China||Department of Cardiology,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China
- 7. Department of Nephrology,Yiyang Central Hospital,Yiyang 413000,China
- 8. Department of Neurosurgery,the First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421001,China
- 折叠
摘要
关键词
succinate accumulation/ATP5F1D/HUVEC pyroptosis/mitochondrial damageKey words
succinate accumulation/ATP5F1D/HUVEC pyroptosis/mitochondrial damage引用本文复制引用
Hong Huang,Huifang Tang,Jian Cui,Dan Tang,Xing Xiang,Jie Mao,Zhe He,Hengjing Hu,Zhangxiu He,Lu He..Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs[J].生物化学与生物物理学报（英文版）,2025,57(12):2011-2021,11.基金项目
This work was supported by the grants from the Natural Science Foundation of Hunan Province(Nos.2023JJ60051 and 2022JJ40393),the Health Research Project of Hunan Provincial Health Commission(Nos.W20241008 and W20243271),the Clinical Research 4310 Program of the First Affiliated Hospital of the University of South China(No.20214310NHYCG03)and the Innovation Platform and Talent Program(No.2023TP1047). （Nos.2023JJ60051 and 2022JJ40393）
