新发传染病电子杂志2025，Vol.10Issue(6)：52-56,5.DOI:10.19871/j.cnki.xfcrbzz.2025.06.008
电磁导航支气管镜辅助肺结节术前定位在HIV感染/AIDS患者中的临床应用
Clinical application of electromagnetic navigation bronchoscopy-assisted preoperative localization of pulmonary nodules in HIV-infected/AIDS patients
摘要
Abstract
Objective To analyze the clinical data of HIV-infected/AIDS patients undergoing preoperative localization of pulmonary nodules with electromagnetic navigation bronchoscopy,summarize its safety and efficacy,and provide evidence for promoting this technique among HIV-infected/AIDS populations.Method A retrospective study included patients with pulmonary nodules and HIV infection/AIDS who visited Chengdu Public Health Clinical Medical Center from September 2023 to December 2024.All patients underwent electromagnetic navigation bronchoscopy-assisted preoperative localization of pulmonary nodules followed by fluorescence-guided thoracoscopic surgery.Baseline data,surgical outcomes,nodule location,density,pathological results,and surgical approaches were collected for statistical description and analysis.Result This study included 17 patients with pulmonary nodules and HIV infection/AIDS.Among them,8 patients had solitary pulmonary nodules,8 had unilateral multiple nodules,and 1 had bilateral multiple nodules.A total of 28 pulmonary nodules were preoperatively localized using electromagnetic navigation bronchoscopy,with an average size of(7.61±3.16)mm.In terms of anatomical distribution,there were 11 nodules(39.29%)in the right upper lobe,3 nodules(10.71%)in the right middle lobe,6 nodules(21.43%)in the right lower lobe,6 nodules(21.43%)in the left upper lobe,and 2 nodules(7.14%)in the left lower lobe.In terms of pathological classification of nodules,there were 10 pure ground-glass nodules(35.71%),14 mixed ground-glass nodules(50.00%),and 4 solid nodules(14.29%).The average distance from the pulmonary nodules to the visceral pleura was(11.41±5.68)mm,and the average procedure duration was(21.29±5.49)min.The localization success rate was 96.4%(27/28),with no related complications occurring.Postoperative pathological results showed that among the 28 preoperatively localized nodules from 17 patients,there were 2 cases of adenocarcinoma in situ(7.14%),10 cases of minimally invasive adenocarcinoma(35.71%),3 cases of invasive adenocarcinoma(10.71%),3 cases of granuloma(10.71%),and 10 cases of inflammatory nodule(35.71%).Conclusion In patients with pulmonary nodules complicated by HIV infection/AIDS,electromagnetic navigation bronchoscopy-assisted preoperative localization of pulmonary nodules offers rapid,safe,and effective positioning while reducing occupational exposure risks for operators.It provides an optimal preoperative localization strategy for this special population and merits clinical promotion and application.关键词
肺结节/HIV感染/艾滋病/术前定位/电磁导航支气管镜Key words
Pulmonary nodules/HIV infection/AIDS/Preoperative localization/Electromagnetic navigation bronchoscopy分类
医药卫生引用本文复制引用
龚胜,李丹,王宁,李刚,刘玉,蒋良双,姚晓军..电磁导航支气管镜辅助肺结节术前定位在HIV感染/AIDS患者中的临床应用[J].新发传染病电子杂志,2025,10(6):52-56,5.基金项目
1.四川省临床重点专科建设项目(2024AXWKP001) （2024AXWKP001）
2.四川省医学会课题项目(S21067) （S21067）
3.四川省科学技术厅重点研发项目(2023YFG0283) （2023YFG0283）
