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首页|期刊导航|药物分析学报(英文)|Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis

Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis

Xinyu Li Ruiqin Yao Jia Ji Jing Li Saisai Li Qiang Luo Maosheng Gu Xin Yin Meng Zhang Hongbin Fan

药物分析学报(英文)2025,Vol.15Issue(11):2744-2759,16.
药物分析学报(英文)2025,Vol.15Issue(11):2744-2759,16.DOI:10.1016/j.jpha.2025.101291

Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis

Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis

Xinyu Li 1Ruiqin Yao 2Jia Ji 2Jing Li 2Saisai Li 2Qiang Luo 2Maosheng Gu 3Xin Yin 3Meng Zhang 4Hongbin Fan5

作者信息

  • 1. Department of Cell Biology and Neurobiology,Xuzhou Key Laboratory of Neurobiology,Xuzhou Medical University,Xuzhou,Jiangsu,221004,China||Department of Neurology,Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,221006,China
  • 2. Department of Cell Biology and Neurobiology,Xuzhou Key Laboratory of Neurobiology,Xuzhou Medical University,Xuzhou,Jiangsu,221004,China
  • 3. Department of Genetic Medicine,Maternity and Child Health Care Hospital Affiliated to Xuzhou Medical University,Xuzhou,Jiangsu,221009,China
  • 4. Department of Urology,Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,221006,China
  • 5. Department of Neurology,Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,221006,China
  • 折叠

摘要

关键词

Epilepsy/Bile acid/Ferroptosis/Cognitive function/FXR/HO-1

Key words

Epilepsy/Bile acid/Ferroptosis/Cognitive function/FXR/HO-1

引用本文复制引用

Xinyu Li,Ruiqin Yao,Jia Ji,Jing Li,Saisai Li,Qiang Luo,Maosheng Gu,Xin Yin,Meng Zhang,Hongbin Fan..Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis[J].药物分析学报(英文),2025,15(11):2744-2759,16.

基金项目

This work was supported by the National Natural Science Foundation of China(Grant No.:82201808)and the Natural Science Foundation of Jiangsu Province(Grant No.:BK20221221).The ex-periments were conducted in the Public Experimental Research Center of Xuzhou Medical University.Graphical abstract was created with BioRender. (Grant No.:82201808)

药物分析学报(英文)

2095-1779

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