湖北科技学院学报（医学版）2026，Vol.40Issue(1)：23-28,6.DOI:10.16751/j.cnki.2095-4646.2025052310
刺梨不同药用部位乙醇提取物清除自由基的活性研究
Free Radical Scavenging Activity of Ethanol Extracts from Different Medicinal Parts of Rosa roxburghii
摘要
Abstract
Objective To explore the free radical scavenging activity of ethanol extracts from different medicinal parts of Rosa rox-burghii.Methods The total phenolic and total flavonoid contents in ethanol extracts from different parts of R.roxburghii were determined,and the scavenging activities against DPPH,ABTS,and·O2-were analyzed.Results In the fruit of R.roxburghii,the total phenolic content of seedless R.roxburghii(DR)(234.17±4.00)μg/mg was significantly higher than that of other parts(P<0.05).The total flavonoid con-tents of whole fruit residue(WRR)and seedless R.roxburghii residue(DRR)were(21.05±0.78)μg/mg and(24.42±3.71)μg/mg,respectively,which were significantly higher than those of other parts in the fruit.In terms of activity,the whole fruit(WR)and DR had sig-nificantly better scavenging activities against DPPH and ABTS free radicals than other parts of the fruit(P<0.05).The scavenging activi-ties of DPPH and ABTS free radicals of ethanol extracts from each part were in a dose-dependent relationship with their total phenolic con-tents.In the·O2-scavenging experiment,the scavenging activity of WR and DR was better than that of the positive drug butylated hydroxy-toluene(BHT)(P<0.05).Conclusion Seedless R.roxburghii(fruit flesh)is the main part of the fruit that contains total phenolic and has the ability to scavenge free radicals.It can be prioritized as a medicinal part for further research on the antioxidant and anti-inflammatory activities of R.roxburghii.关键词
刺梨/自由基清除活性/DPPH/ABTS/·O2-Key words
Rosa roxburghii/Free radical scavenging activity/DPPH/ABTS/·O2-分类
医药卫生引用本文复制引用
程文敬,万哲,管志威,宋琳,董熙瑞,王舒可,莫启贵..刺梨不同药用部位乙醇提取物清除自由基的活性研究[J].湖北科技学院学报（医学版）,2026,40(1):23-28,6.基金项目
湖北科技学院糖尿病心脑血管病变重点实验室糖尿病专项基金(2022TNB06) （2022TNB06）
湖北科技学院校内博士科研启动项目(BK202332) （BK202332）
