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Decoding protein dynamics with limited proteolysis coupled to mass spectrometry:A comprehensive review

Zilu Zhao Xue Zhang Xin Dong Zhanying Hong

药物分析学报(英文)2025,Vol.15Issue(12):2796-2806,11.
药物分析学报(英文)2025,Vol.15Issue(12):2796-2806,11.DOI:10.1016/j.jpha.2025.101319

Decoding protein dynamics with limited proteolysis coupled to mass spectrometry:A comprehensive review

Decoding protein dynamics with limited proteolysis coupled to mass spectrometry:A comprehensive review

Zilu Zhao 1Xue Zhang 1Xin Dong 1Zhanying Hong2

作者信息

  • 1. School of Medicine,Shanghai University,Shanghai,200444,China
  • 2. School of Pharmacy,Naval Medical University,Shanghai,200433,China
  • 折叠

摘要

关键词

Limited proteolysis/Mass spectrometry/Drug targets/Structural proteomics/Conformational change

Key words

Limited proteolysis/Mass spectrometry/Drug targets/Structural proteomics/Conformational change

引用本文复制引用

Zilu Zhao,Xue Zhang,Xin Dong,Zhanying Hong..Decoding protein dynamics with limited proteolysis coupled to mass spectrometry:A comprehensive review[J].药物分析学报(英文),2025,15(12):2796-2806,11.

基金项目

This work was supported by the National Natural Science Foundation of China(Grant No.:22304002).Fig.3B was drawn by using Figdraw. (Grant No.:22304002)

药物分析学报(英文)

2095-1779

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