中国塑料2026，Vol.40Issue(1)：43-49,7.DOI:10.19491/j.issn.1001-9278.2026.01.006
抗菌聚乙烯醇纳米纤维敷料制备及性能研究
Preparation and performance characterization of antibacterial polyvinyl alcohol nanofiber dressing
郭欣 1岑婷婷 2徐海云 1赵晓颖 1项爱民1
作者信息
- 1. 北京工商大学轻工科学与工程学院,北京 100048
- 2. 首钢贵阳特殊钢有限责任公司,贵阳 550000
- 折叠
摘要
Abstract
Wound dressings play a critical role in the healing process.This study developed a series of wound dressings with potent and long-lasting antimicrobial properties using an electrospinning technique.Polyvinyl alcohol(PVA)served as the substrate,loaded with several antimicrobial agents.To enhance the antimicrobial performance of the PVA/Ag⁺nanofiber membrane,wormwood(WW)decoction was incorporated as a secondary agent,producing a PVA/Ag⁺/WW composite nanofiber membrane.Fourier-transform infrared spectroscopy confirmed the successful incorporation of worm-wood's active antimicrobial components into the fibers.Scanning electron microscopy further verified the presence of wormwood within the material.The incorporation of wormwood improved the membrane's wettability,reducing the wa-ter contact angle from 50.5 ° to 23.5 °.Antimicrobial assays demonstrated that with a wormwood decoction concentra-tion of 80%,the inhibition zone diameters for the PVA/Ag⁺/WW membrane against Staphylococcus aureus,Escherich-ia coli,and Candida albicans were 16.02 mm,16.29 mm,and 16.22 mm,respectively.Furthermore,the nanofiber membranes maintained effective antimicrobial activity for five weeks.In conclusion,this work successfully combined sil-ver ions and wormwood decoction to create a high-performance nanofiber membrane with enhanced and sustained antimi-crobial efficacy,showing great promise for application in wound dressings and other medical fields.关键词
静电纺丝/聚乙烯醇/艾草/抗菌伤口敷料Key words
electrospinning/polyvinyl alcohol/artemisia argyi/antibacterial wound dressing分类
化学化工引用本文复制引用
郭欣,岑婷婷,徐海云,赵晓颖,项爱民..抗菌聚乙烯醇纳米纤维敷料制备及性能研究[J].中国塑料,2026,40(1):43-49,7.
