中国医学创新2026,Vol.23Issue(1):69-72,4.DOI:10.3969/j.issn.1674-4985.2026.01.016
人干扰素α2b阴道泡腾片联合阴道用乳杆菌活菌胶囊治疗子宫颈HPV感染的效果
Effect of Human Interferon α2b Vaginal Effervescent Tablets Combined with Live Lactobacillus Capsule for Vaginal Use in the Treatment of Cervical HPV Infection
钟玉 1颜江 1程湘怡 1刘瑶2
作者信息
- 1. 萍乡赣西肿瘤医院妇科 江西 萍乡 337099
- 2. 萍乡矿业集团有限责任公司总医院药剂科 江西 萍乡 337099
- 折叠
摘要
Abstract
Objective:To analyze the effect of Human Interferon α2b Vaginal Effervescent Tablets combined with Live Lactobacillus Capsule for Vaginal Use in the treatment of cervical human papilloma virus(HPV)infection.Method:A total of 92 patients with cervical HPV infection admitted to Pingxiang Ganxi Cancer Hospital from January 2023 to September 2024 were included and divided into a control group(n=46)and an observation group(n=46)using a random number table method.The control group was treated with Human Interferon α2b Vaginal Effervescent Tablets,based on this,the observation group combined with Live Lactobacillus Capsule for Vaginal Use.Both groups were treated for 3 months.The efficacy,vaginal microecology,inflammatory markers[IL-6,IL-4,interferon-γ(IFN-γ)],and incidence of adverse reactions between two groups were compared.Result:Compared with the control group(80.43%),the total effective rate of the observation group(95.65%)after treatment was higher(P<0.05).Compared with the control group,the normal rate of pH value,the negative rate of leukocyte esterase and the negative rate of hydrogen peroxide after treatment in the observation group were higher(P<0.05).After treatment,the levels of IL-6 and IL-4 in the observation group were lower than those in the control group,and the levels of IFN-γ was higher than that in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Human Interferon α2b Vaginal Effervescent Tablets combined with Live Lactobacillus Capsule for Vaginal Use have a definite therapeutic effect on cervical HPV infection,which can promote the recovery of vaginal microecological function and alleviate inflammatory responses.关键词
人乳头瘤病毒感染/人干扰素α2b阴道泡腾片/阴道用乳杆菌活菌胶囊/阴道微生态Key words
Human papilloma virus infection/Human Interferon α2b Vaginal Effervescent Tablets/Live Lactobacillus Capsule for Vaginal Use/Vaginal microecology引用本文复制引用
钟玉,颜江,程湘怡,刘瑶..人干扰素α2b阴道泡腾片联合阴道用乳杆菌活菌胶囊治疗子宫颈HPV感染的效果[J].中国医学创新,2026,23(1):69-72,4.