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铁死亡在蛛网膜下腔出血中的研究进展

崔皓尘 尹艳玲

中国脑血管病杂志2026,Vol.23Issue(1):67-74,8.
中国脑血管病杂志2026,Vol.23Issue(1):67-74,8.DOI:10.3969/j.issn.1672-5921.2026.01.009

铁死亡在蛛网膜下腔出血中的研究进展

Research progress on ferroptosis in subarachnoid hemorrhage

崔皓尘 1尹艳玲1

作者信息

  • 1. 100069 北京,首都医科大学基础医学院神经生物学系
  • 折叠

摘要

Abstract

Subarachnoid hemorrhage(SAH)is a severe cerebrovascular disease with high mortality and disability rates which significantly affect patient prognosis.Ferroptosis,a type of cell death characterized by iron accumulation and lipid peroxidation,has garnered increasing attention in primary brain injury and secondary brain injury following SAH.To provide new insights for both basic research and clinical treatment of SAH,this article summarized the characteristics,the relative signaling pathways of ferroptosis after SAH,ferroptosis-mediated alterations in neuron-glia interactions,and therapeutic strategies targeting ferroptosis.

关键词

蛛网膜下腔出血/铁死亡/神经保护/铁代谢/综述

Key words

Subarachnoid hemorrhage/Ferroptosis/Neuroprotection/Iron metabolism/Review

引用本文复制引用

崔皓尘,尹艳玲..铁死亡在蛛网膜下腔出血中的研究进展[J].中国脑血管病杂志,2026,23(1):67-74,8.

基金项目

国家自然科学基金(82471213) (82471213)

中国脑血管病杂志

1672-5921

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