中医药学报2026，Vol.54Issue(2)：88-92,5.DOI:10.19664/j.cnki.1002-2392.260040
自拟宣肺通窍汤联合穴位贴敷对过敏性鼻炎患儿炎症因子、免疫功能及预后影响
The Influence of Self-Designed Xuanfei Tongqiao Decoction Combined with Acupoint Application on Inflammatory Factors,Immune Function and Prognosis of Children with Allergic Rhinitis
摘要
Abstract
Objective:To analyze the application value of the self-designed Xuanfei Tongqiao Decoction combined with acupoint application in the clinical efficacy,inflammatory factors,immune function and prognosis of children with allergic rhinitis.Method:The research subjects were 186 children with allergic rhinitis who were diagnosed and treated in our hospital from September 2022 to August 2024.They were divided into the control group(n=93)and the observation group(n=93)by the random number table method.The control group was treated with loratadine syrup,while the observation group was treated with self-designed Xuanfei Tongqiao Decoction combined with acupoint application.Both groups were treated for 2 months.Compare the clinical efficacy of the two groups;The levels of inflammatory factors,immune function indicators,TCM syndrome scores and quality of life scores of the two groups of children before and after treatment were compared;Compare the incidence of adverse reactions after treatment between the two groups of children.Results:Compared with the control group,the total effective rate of clinical treatment of the children was significantly increased in the observation group(P<0.01).After treatment,the levels of C-reactive protein(CRP),tumor necrosis factor α(TNF-α)and interleukin-6(IL-6)were significantly decreased in the observation group compared with the control group(P<0.01).Compared with the control group,the immunoglobulin E(IgE)and eosinophils(EOS)counts were significantly decreased in the observation group after treatment,and the CD4+/CD8+levels were significantly increased in the observation group(P<0.01).Compared with control group,TCM syndrome score and allergic rhinitis Quality of Life questionnaire(RQLQ)score were significantly decreased in observation group after treatment(P<0.01).Compared with the control group,the total incidence of adverse reactions after treatment was significantly reduced in the observation group(P<0.05).Conclusion:The self-proposed Xuanfei Tongqiao Decoction combined with acupoint application has a high clinical efficacy for children with allergic rhinitis.It can effectively improve the inflammatory response,immune function,TCM syndrome score and quality of life of the children,and has high safety.关键词
宣肺通窍汤/穴位贴敷/过敏性鼻炎/免疫功能/预后Key words
Xuanfei Tongqiao Decoction/Acupoint application/Allergic rhinitis/Immune function/Prognosis分类
医药卫生引用本文复制引用
时丹丹,陈晶,李秋侠,李欢欢,孙炳霞..自拟宣肺通窍汤联合穴位贴敷对过敏性鼻炎患儿炎症因子、免疫功能及预后影响[J].中医药学报,2026,54(2):88-92,5.基金项目
江苏省中医药科技发展计划项目(Z2022132) （Z2022132）
2022年度宿迁科技计划资助市级指导性科技项目(Z2022091) （Z2022091）
