中国斜视与小儿眼科杂志2025，Vol.33Issue(4)：1-4,4.DOI:10.3969/J.ISSN.1005-328X.2025.04.001
斜视矫正术后眼表特征和泪液炎性因子水平分析
Analysis of ocular surface characteristics and tear inflammatory factor levels after strabismus correction surgery
摘要
Abstract
Objective To investigate the recovery of ocular surface damage and the levels of inflammatory cytokines in tears after strabismus surgery.Methods Patients over 16 years old with exotropia were included.Preoperative and postop-erative follow-ups were conducted at 1 day,1 week,and l month.Ocular Surface Disease Index(OSDI)score,tear break-up time(TBUT),corneal fluorescein staining(CFS)score,and levels of inflammatory cytokines in tears were analyzed.Results None of the patients had dry eye symptoms before surgery.TBUT was shortened at 1 day postoperatively and returned to the preoperative level at 1 month.CFS score increased at 1 day postoperatively,but the difference was not statistically significant(P=0.368).Levels of inflammatory cytokines in tears increased at 1 day postoperatively,with statistically significant differences in IL-6,TNF-α,and leptin,but not in IL-1β(P=0.52).The levels returned to the preoperative level at 1 month.Conclusion Tear film stability is impaired and the levels of inflammatory cytokines in tears are increased after strabismus correction surgery,but both return to the preoperative level at 1 month.关键词
斜视/手术/眼表/泪液因子Key words
Strabismus/Surgery/Ocular surface/Tear factors引用本文复制引用
刘容均,刘海华,李巧娴..斜视矫正术后眼表特征和泪液炎性因子水平分析[J].中国斜视与小儿眼科杂志,2025,33(4):1-4,4.基金项目
北京大学第一医院青年临床研究专项 （）
