动物营养学报2025，Vol.37Issue(12)：8133-8143,11.DOI:10.12418/CJAN2025.663
山奈酚通过"菌群-代谢-免疫轴"调控动物肠道健康和生产性能的作用机制及研究进展
Mechanism and Research Progress of Kaempferol Regulating Animal Intestinal Health and Performance through"Microbiota-Metabolism-Immunity Axis"
摘要
Abstract
As a typical natural flavonoid,kaempferol has emerged as a key research focus in the field of natural feed additives due to its potent antioxidant,anti-inflammatory properties and synergistic effect in regulating in-testinal microbiota balance.Kaempferol achieves free radical scavenging and targeted regulatory functions through its active groups(2,3-conjugated double bond,4-ketone group,and 3′,4′-catechol structure).Through microbiota-mediated glycoside hydrolysis and metabolite generation,it remodels microbial community structure,activates immune signaling pathways,enhances intestinal barrier function,and suppresses inflamma-tory responses.Kaempferol has demonstrated significant application potential in disease prevention and control,growth performance improvement,and reproductive performance enhancement in livestock,poultry and aquatic farming.This review comprehensively analyzes the mechanisms of kaempferol from the perspective of multi-level homeostatic regulation along the"microbiota-metabolism-immunity axis",aiming to provide a theoretical foundation for the development of efficient and safe green feed additives and promote the advancement of green and healthy breeding.关键词
山奈酚/肠道菌群/代谢/免疫/动物健康Key words
kaempferol/intestinal microbiota/metabolism/immunity/animal health分类
农业科技引用本文复制引用
刘翔雨,孙秀柱,任战军,王淑辉..山奈酚通过"菌群-代谢-免疫轴"调控动物肠道健康和生产性能的作用机制及研究进展[J].动物营养学报,2025,37(12):8133-8143,11.基金项目
陕西省级农业科技创新专项资金项目(20231494) （20231494）
陕西省林科院科技创新计划专项(SXLK2021-0219) （SXLK2021-0219）
