中国耳鼻咽喉头颈外科2025，Vol.32Issue(11)：709-713,5.DOI:10.16066/j.1672-7002.2025.11.006
侵袭与非侵袭混合型真菌性鼻窦炎临床特征探讨
Clinical features of mixed invasive and non-invasive fungal rhinosinusitis
王明婕 1孙炎 1石颖 1李骋1
作者信息
- 1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),北京 100730
- 折叠
摘要
Abstract
OBJECTIVE Aimed to characterize the clinical features of invasive and non-invasive mixed FRS and explore risk factors for disease progression.METHODS A retrospective case control study was performed on 96 confirmed FRS patients(June 2022-May 2024),including 32 invasive FRS(IFRS)cases and 64 fungal ball rhinosinusitis(FBR).Clinical characteristic were all analyzed.RESULTS Among 96 FRS patients,5 cases exhibited mixed fungal rhinosinusitis(MFS)features.Comparative analysis revealed:MFS cases predominantly were all combined with poorly controlled long-standing diabetes(mean duration 12.3 years).Clinical manifestations:Distinctive presentations included headache(60%),and visual impairment(60%).Diabetes mellitus and elevated HCRP independently predicted FB-to-IFRS progression.CONCLUSION The invasive and non-invasive mixed fungal rhinosinusitis typically occurs in elderly patients with a long-term history of poor controlled diabetes.This study indicates that elderly patients with long-term diabetes should actively undergo screening and treatment for fungal ball sinusitis,in order to prevent the progression of fungal ball sinusitis to chronic invasive fungal sinusitis.关键词
鼻窦炎/侵袭性真菌感染/肉芽肿/侵袭性真菌性鼻窦炎/非侵袭性真菌性鼻窦炎/真菌球性鼻窦炎/慢性肉芽肿性侵袭性真菌性鼻窦炎Key words
Sinusitis/Invasive Fungal Infections/Granuloma/invasive fungal sinusitis/non-invasive fungal sinusitis/fungal ball sinusitis/chronic invasive granulomatous fungal sinusitis引用本文复制引用
王明婕,孙炎,石颖,李骋..侵袭与非侵袭混合型真菌性鼻窦炎临床特征探讨[J].中国耳鼻咽喉头颈外科,2025,32(11):709-713,5.
