法医学杂志2025，Vol.41Issue(5)：443-455,13.DOI:10.12116/j.issn.1004-5619.2025.550403
皮肤微生物组:拓展法医学证据维度及面临的挑战
Skin Microbiome:Expanding Dimensions and Challenges in Forensic Evidence
张晗 1黄馨 2陈安琪 1陈吉 2路艳芳 1曾建业 2王翔1
作者信息
- 1. 复旦大学法庭科学研究院,上海 200032
- 2. 复旦大学法医学与法庭科学学院,上海 200032
- 折叠
摘要
Abstract
The skin microbiome,characterized by its vast abundance,high diversity,pronounced indi-vidual specificity,and dynamic traceability,serves as a significant biological marker of the host.Its composition and variation are influenced by both the host's physiological states and external environ-mental factors,exhibiting a close"mirror"relationship with host phenotypes.This unique"microbial fingerprint"not only expands the sources of forensic evidence but also offers new perspectives and op-portunities for the advancement of forensic research and practice.This paper reviews the physiological and structural foundations underlying skin microbial diversity and the mechanisms that shape individual specificity,analyzes its unique advantages and technical approaches in forensic applications,outlines re-cent research progress,explores the future potential and major challenges of using skin microbiome markers in forensic science,and proposes practical recommendations.关键词
法医学/法医微生物学/皮肤微生物组/微生物指纹/内外环境因素/综述Key words
forensic medicine/forensic microbiology/skin microbiome/microbial fingerprint/external and internal environmental factors/review分类
医药卫生引用本文复制引用
张晗,黄馨,陈安琪,陈吉,路艳芳,曾建业,王翔..皮肤微生物组:拓展法医学证据维度及面临的挑战[J].法医学杂志,2025,41(5):443-455,13.
