法医学杂志2025,Vol.41Issue(5):482-493,12.DOI:10.12116/j.issn.1004-5619.2025.550501
法医微生物分析规范化的建议
Recommendations for the Standardization of Forensic Microbiological Analysis
摘要
Abstract
With advances in microbiome research and the continuous advancement of detection tech-nologies,the application of microorganisms in forensic medicine has become increasingly widespread,covering areas such as individual identification,body fluid source inference,biogeographical analysis,postmortem interval estimation,and determination of the cause and location of death.However,due to the lack of a comprehensive standardized system,batch effects and inter-laboratory differences have led to low reproducibility of analysis results.This problem is particularly evident in low-quality forensic samples,which compromise the reliability and evidential value of forensic microbiological analyses.Therefore,based on domestic and international research progress and practical experience,this paper systematically summarizes and discusses the standardization of forensic microbiological analysis,aiming to improve the reliability of results and promote the standardization of forensic microbiological analysis.关键词
法医学/法医微生物学/核酸分析/可重复性/规范化Key words
forensic medicine/forensic microbiology/nucleic acid analysis/reproducibility/standardiza-tion分类
医药卫生引用本文复制引用
刘志勇,孙宏钰,刘超,赵兴春,陈玲,乌日嘎,苑美青,陈晓晖,赵建,徐曲毅,刘长晖..法医微生物分析规范化的建议[J].法医学杂志,2025,41(5):482-493,12.基金项目
国家自然科学基金重大项目(82293655,82293650) (82293655,82293650)
国家自然科学基金面上项目(82271927,82371901) (82271927,82371901)
公安部鉴定中心开放课题(2025FGKFKT09) (2025FGKFKT09)