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法医微生物分析规范化的建议

刘志勇 孙宏钰 刘超 赵兴春 陈玲 乌日嘎 苑美青 陈晓晖 赵建 徐曲毅 刘长晖

法医学杂志2025,Vol.41Issue(5):482-493,12.
法医学杂志2025,Vol.41Issue(5):482-493,12.DOI:10.12116/j.issn.1004-5619.2025.550501

法医微生物分析规范化的建议

Recommendations for the Standardization of Forensic Microbiological Analysis

刘志勇 1孙宏钰 2刘超 1赵兴春 3陈玲 4乌日嘎 5苑美青 1陈晓晖 4赵建 2徐曲毅 2刘长晖2

作者信息

  • 1. 中山大学中山医学院法医学系,广东 广州 510080
  • 2. 广州市刑事科学技术研究所,广东 广州 510442
  • 3. 广东省毒品实验技术中心 国家毒品实验室广东分中心,广东 广州 510230
  • 4. 公安部鉴定中心,北京 100038
  • 5. 南方医科大学法医学院,广东 广州 510515
  • 折叠

摘要

Abstract

With advances in microbiome research and the continuous advancement of detection tech-nologies,the application of microorganisms in forensic medicine has become increasingly widespread,covering areas such as individual identification,body fluid source inference,biogeographical analysis,postmortem interval estimation,and determination of the cause and location of death.However,due to the lack of a comprehensive standardized system,batch effects and inter-laboratory differences have led to low reproducibility of analysis results.This problem is particularly evident in low-quality forensic samples,which compromise the reliability and evidential value of forensic microbiological analyses.Therefore,based on domestic and international research progress and practical experience,this paper systematically summarizes and discusses the standardization of forensic microbiological analysis,aiming to improve the reliability of results and promote the standardization of forensic microbiological analysis.

关键词

法医学/法医微生物学/核酸分析/可重复性/规范化

Key words

forensic medicine/forensic microbiology/nucleic acid analysis/reproducibility/standardiza-tion

分类

医药卫生

引用本文复制引用

刘志勇,孙宏钰,刘超,赵兴春,陈玲,乌日嘎,苑美青,陈晓晖,赵建,徐曲毅,刘长晖..法医微生物分析规范化的建议[J].法医学杂志,2025,41(5):482-493,12.

基金项目

国家自然科学基金重大项目(82293655,82293650) (82293655,82293650)

国家自然科学基金面上项目(82271927,82371901) (82271927,82371901)

公安部鉴定中心开放课题(2025FGKFKT09) (2025FGKFKT09)

法医学杂志

OA北大核心

1004-5619

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