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Itaconate facilitates methane-induced Nrf2 pathway activation for mitigating liver ischemia and reperfusion injury

Tianyi Zhang Danfeng Fan Kewei Qin Hongtao Lu Linwei Zhao Kexin Liu Pei Zhang Qiang Sun Zhouheng Ye

国际肝胆健康（英文）Issue(1)：26-33,8.

国际肝胆健康（英文）Issue(1)：26-33,8.DOI:10.1016/j.iliver.2025.100144

Itaconate facilitates methane-induced Nrf2 pathway activation for mitigating liver ischemia and reperfusion injury

Tianyi Zhang ¹Danfeng Fan ²Kewei Qin ³Hongtao Lu ⁴Linwei Zhao ⁵Kexin Liu ⁵Pei Zhang ⁶Qiang Sun ²Zhouheng Ye⁷

作者信息

1. Medical Innovation Research Department of PLA General Hospital,Beijing 100853,China
2. Department of Hyperbaric Medicine,The Sixth Medical Center of PLA General Hospital,Beijing 100048,China
3. College of Otolaryngology Head and Neck Surgery,The Sixth Medical Center of PLA General Hospital,Beijing 100048,China
4. Department of Naval Medicine,Naval Medical University,Shanghai 200433,China
5. School of Medicine,South China University of Technology,Guangzhou 518055,China
6. Department of Radiation Oncology,The Fifth Medical Center of PLA General Hospital,Beijing 100071,China
7. Department of Special Operations Medicine,The Sixth Medical Center of PLA General Hospital,Beijing 100048,China
折叠

摘要

关键词

Methane/Itaconate/Nrf2/Ischemia/Reperfusion/Acod1/Liver

Key words

Methane/Itaconate/Nrf2/Ischemia/Reperfusion/Acod1/Liver

引用本文复制引用

Tianyi Zhang,Danfeng Fan,Kewei Qin,Hongtao Lu,Linwei Zhao,Kexin Liu,Pei Zhang,Qiang Sun,Zhouheng Ye..Itaconate facilitates methane-induced Nrf2 pathway activation for mitigating liver ischemia and reperfusion injury[J].国际肝胆健康（英文）,2025,(1):26-33,8.

基金项目

This research was funded by National Natural Science Foundation of China(82000587,82202382)and the Beijing Municipal Natural Science Foundation(7242135). （82000587,82202382）

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