国际神经病学神经外科学杂志2025,Vol.52Issue(6):76-81,6.DOI:10.16636/j.cnki.jinn.1673-2642.2025.06.011
超低温保存自体颅骨修补术后早期癫痫发作的影响因素分析
Risk factors for early postoperative seizures after cryopreserved autologous cranioplasty
李佳宇 1曹西 1陈靓 1霍坤良 1杨子茵1
作者信息
- 1. 成都医学院第二附属医院·核工业四一六医院神经外科,四川 成都 610000
- 折叠
摘要
Abstract
Objective To investigate the risk factors for early postoperative seizures(EPS)after cryopreserved autologous cranioplasty.Methods A retrospective analysis was performed for the clinical data of 282 patients who underwent cryopreserved autologous cranioplasty in The Second Affiliated Hospital of Chengdu Medical College&Nuclear Industry 416 Hospital from January 2012 to June 2025.The clinical manifestations of seizures within 7 days after surgery were used to assess early seizures,and then the patients were divided into seizure group and non-seizure group.The multivariate logistic regression analysis was used to identify the influencing factors for EPS.Results There were 43 patients with EPS,resulting in an incidence rate of 15.25%.Skin flap depression(odds ratio[OR]=4.811,95%confidence interval[CI]:1.858-12.459,P<0.05),skin flap protrusion(OR=4.529,95%CI:1.608-12.755,P<0.05),and postoperative hemorrhage or fluid accumulation(OR=2.911,95%CI:1.280-6.622,P<0.05)were associated with EPS after autologous cranioplasty.Conclusions Skin flap depression,skin flap protrusion,and postoperative hemorrhage or fluid accumulation are risk factors for EPS after cryopreserved autologous cranioplasty.关键词
自体颅骨/颅骨修补术/术后早期癫痫发作/危险因素Key words
autologous skull bone/cranioplasty/early postoperative seizures/risk factors分类
医药卫生引用本文复制引用
李佳宇,曹西,陈靓,霍坤良,杨子茵..超低温保存自体颅骨修补术后早期癫痫发作的影响因素分析[J].国际神经病学神经外科学杂志,2025,52(6):76-81,6.