甘肃中医药大学学报2025，Vol.42Issue(6)：55-61,7.DOI:10.16841/j.issn1003-8450.2025.06.08
4种甘肃特色中药材金属元素分析及健康风险评估
Metal element analysis and health risk assessment of four distinctive Chinese medicinal materials from Gansu
摘要
Abstract
Objective To determine the metal element content in four distinctive Chinese medicinal materials from Gansu Province,providing a scientific basis for their safety evaluation and quality control.Methods Astraga-lus membranaceus,Codonopsis pilosula,Rheum palmatum,and Angelica sinensis cultivated in five villages of Bali Town,Tanchang County,Longnan City,Gansu Province,were collected.Flame atomic absorption spectroscopy(FAAS)and atomic fluorescence spectroscopy(AFS)were employed to measure common metal elements.The pol-lution levels of heavy metals were analyzed using the single-factor pollution index and Nemerow composite pollution index,while Target Hazard Quotient(THQ)and Carcinogenic Risk(CR)assessments were conducted for health risk evaluation.Results The contents of detected elements varied among the medicinal materials.The average levels of copper(Cu),arsenic(As),mercury(Hg),and lead(Pb)were lower than the limits specified in the Chinese Phar-macopoeia(Part Ⅰ)2020 edition and other international standards.Both the single-factor and Nemerow composite pollution indices indicated that heavy metal contents in the four medicinal materials were within safe levels.THQ assessment suggested that only As in Astragalus membranaceus posed a minor health risk,while other heavy metals showed no hazards.CR evaluation confirmed no carcinogenic risk in the four medicinal materials from all five villages.Conclusion The heavy metal content in the four medicinal materials from Bali Town is relatively low.However,attention should be paid to potential heavy metal accumulation during cultivation to ensure clinical medi-cation safety.关键词
甘肃/中药/重金属/火焰原子吸收/原子荧光/健康风险评估Key words
Gansu/Chinese medicinal materials/heavy metals/flame atomic absorption spectroscopy(FAAS)/atomic fluorescence spectroscopy(AFS)/health risk assessment分类
医药卫生引用本文复制引用
赵静,陈晖,谢永强,赵小强,张浩波..4种甘肃特色中药材金属元素分析及健康风险评估[J].甘肃中医药大学学报,2025,42(6):55-61,7.基金项目
甘肃省教育厅创新基金项目(2022A-070) （2022A-070）
甘肃中医药大学扶贫科研项目(2019FPZX-4) （2019FPZX-4）
甘肃省就业创业研究课题(2021-50). （2021-50）
