甘肃中医药大学学报2025，Vol.42Issue(6)：62-67,6.DOI:10.16841/j.issn1003-8450.2025.06.09
基于藏医古籍文献的失眠症藏药方剂配伍规律及药性特征研究
Research on the compatibility rules and medicinal properties of Tibetan prescriptions for insomnia based on ancient Tibetan medical literature
摘要
Abstract
Objective To explore the compatibility patterns and medicinal properties of Tibetan medicinal for-mulations for treating insomnia as recorded in ancient Tibetan medical texts.Methods Formulations primarily in-dicated for insomnia in ancient Tibetan medical literature were collected.Frequency statistics were performed using Microsoft Excel 2019,while descriptive statistics,factor analysis,and cluster analysis were conducted with SPSS 25.0.A drug association clustering network diagram was generated using Gephi 0.9.2,and association rule analysis of drugs was carried out with IBM SPSS Modeler 18.0.Results A total of 81 Tibetan medicinal formulations for treating insomnia were screened,involving 86 medicinal ingredients.High-frequency drugs included Myristica fra-grans,Cuminum cyminum,milk,Syzygium aromaticum,and Elettaria cardamomum.Complex network analysis iden-tified Myristica fragrans,Terminalia chebula,Aconitum ludlowii,Dolomiaea souliei,Aquilaria agallocha,and Syzy-gium aromaticum as core medications.Cluster analysis categorized the drugs into five groups:C1 primarily consisted of drugs for warming the stomach,strengthening the spleen,promoting digestion,and calming the heart,with effects on treating rLung disorders and heart diseases;C2 included drugs for promoting digestion and dispelling cold,mainly targeting rLung and Badkan disorders;C3 comprised drugs for clearing heat,dispelling cold,and relieving pain;C4 mainly consisted of mind-refreshing and tranquilizing drugs;C5 mainly consisted of stomach-warming,cold-dis-pelling,and digestion-promoting drugs.Factor analysis extracted six common factors,reflecting the common use of syndrome differentiation and compatibility in Tibetan medicine for insomnia,focusing on eliminating rLung,warming the stomach,dispelling cold,strengthening the spleen,relieving pain,and treating heart and life channel diseases.In terms of medicinal properties,the primary tastes of the relevant drugs were pungent and sweet,with the post-diges-tive taste predominantly warm.The medicinal properties are predominantly hot and moist;the therapeutic effects are mainly characterized by moistening,heaviness,and sharpness.Conclusion The core mechanism of Tibetan medi-cine in treating insomnia lies in harmonizing the disorders of rLung and mKhris-pa to achieve heart-calming,mind-tranquilizing,sedative,analgesic,antidepressant,and anti-anxiety effects.Simultaneously,emphasis is placed on using gastrointestinal-regulating drugs to improve digestive function and stomach heat,thereby promoting the absorp-tion of food essence and the excretion of waste.By harmonizing the three humors and suppressing pain,insomnia symptoms are effectively alleviated.关键词
失眠症/藏药/方剂配伍/药性/用药规律Key words
insomnia/Tibetan medicine/formulation compatibility/medicinal properties/medication patterns分类
医药卫生引用本文复制引用
英木草,公保甲,普华加,贡保东知..基于藏医古籍文献的失眠症藏药方剂配伍规律及药性特征研究[J].甘肃中医药大学学报,2025,42(6):62-67,6.基金项目
甘肃中医药大学2024年教学研究与改革项目(YBXM-2024-35) （YBXM-2024-35）
甘肃省教育厅科技创新项目(2025QB-071) （2025QB-071）
甘肃(甘南)藏医药"医-药-护"研究与转化协同创新中心阶段性成果. （甘南）
