中国实用神经疾病杂志2026，Vol.29Issue(1)：26-31,6.DOI:10.12083/SYSJ.250851
听神经瘤显微切除术中多模式神经电生理监测的效果
Effect of intraoperative multimodal neurophysiological monitoring during microdissection of acoustic neuroma
摘要
Abstract
Objective To investigate the effect of intraoperative application of multimodal neurophysiological monitoring during microdissection of acoustic neuroma.Methods A retrospective selection was made of 190 patients with acoustic neuroma admitted to the First People's Hospital of Chenzhou and Xiangya Hospital of Central South University from January 2021 to January 2025,with 95 cases in the control group and 95 cases in the study group.The control group underwent simple microdissection,while the study group was combined with multi-modal neurophysiological monitoring on the basis of the control group.The two groups were compared in terms of surgical indexes,pain level,hearing,facial nerve function,complication rate,Glasgow outcome scale(GOS)score and quality of life.Results Intraoperative bleeding,area of posterior labial abrasion of the internal auditory canal,and visual analogue scale(VAS)score were lower in the study group than those in the control group(t=4.499,30.273,44.644,respectively,P＜0.001),operation time was shorter than that in the control group(t=3.035,P=0.003),and the rate of complete tumour resection was higher than that in the control group(90.53％vs 75.79％,x2=7.692,P=0.021).At 1 month postoperatively,the pure tone mean hearing threshold(PTA)of the study group was lower than that of the control group(t=9.283,P＜0.001),and the audiological grading was significantly better than that of the control group(x2=22.741,P＜0.001).At 6 months postoperatively,House-Brackmann grading was significantly better in the study group than that in the control group(x2=8.311,P=0.040).The complication rate was lower in the study group than that in the control group(3.16％vs 11.58％,x2=4.935,P=0.026).At 6 months postoperatively,GOS score and SF-36 score were higher in the study group than those in the control group(t=6.584,8.642,respectively,P＜0.001).Conclusion The intraoperative application of multimodal neurophysiological monitoring during microdissection of acoustic neuroma can effectively shorten the operation time,enhance the rate of total tumour resection,protect the patients' hearing and facial nerve function,and improve the patients' short-term prognosis and quality of life.关键词
听神经瘤/显微切除术/多模式神经电生理监测/疼痛/听力/面神经功能Key words
Acoustic neuroma/Microtomy/Multimodal neurophysiological monitoring/Pain level/Hearing/Facial nerve function分类
医药卫生引用本文复制引用
邓陈浩,叶友忠,唐国强,袁健,李鹃,李明松..听神经瘤显微切除术中多模式神经电生理监测的效果[J].中国实用神经疾病杂志,2026,29(1):26-31,6.基金项目
郴州市科学技术局科技发展计划项目(编号:ZDYF2020109) （编号:ZDYF2020109）
