中国实用神经疾病杂志2026，Vol.29Issue(1)：43-47,5.DOI:10.12083/SYSJ.250426
神经内镜下经鼻蝶入路垂体瘤切除术对老年垂体瘤患者垂体视觉及嗅觉功能的影响
Effect of transsphenoidal neuroendoscopic pituitary tumor resection under neuroendoscope on pituitary,visual and olfactory function in elderly patients with pituitary tumor
摘要
Abstract
Objective To investigate the effects of transsphenoidal pituitary tumor resection(TPTR)under neuroendoscope on pituitary function,visual function,olsmell function and complications in elderly patients with pituitary tumor.Methods Totally 79 elderly patients with pituitary tumor who underwent surgical treatment in the Nanyang Second General Hospital from January 2020 to June 2023 were retrospectively selected.They were divided into microscope group(40 cases)and neuroendoscope group(39 cases).Perioperative indexes,total tumor resection rate,complications,pituitary function indexes(serum TSH,HGH,ACTH level),visual function indexes(VFI,PSD value,MD value)and olfactory recognition domain were compared between the microscope group and the neuroendoscope group.Results In the neuroendoscopy group,the operation time and hospitalization days were shorter than those in the microscope group,and the total intraoperative blood loss was less than that in the microscope group(P＜0.05).The total tumor resection rate in the neuroendoscopy group was higher than that in the microscope group(89.74％vs 70.00％),and the total incidence of postoperative complications was lower than that in the microscope group(5.13％vs 22.50％,x2=4.766,4.972,respectively,P＜0.05).After 1 month of operation,serum TSH,ACTH and HGH levels in the neuroendoscopy group were lower than those in the microscope group(P＜0.05),the VFI and MD values in the neuroendoscopy group were higher than those in the microscope group,while the PSD values and olfactory recognition domain were lower than those in the microscope group(P＜0.05).Conclusion Compared with TPTR under microscope,TPTR under neuroendoscope can further shorten the operation time,reduce the total intraoperative blood loss,increase the total tumor resection rate,reduce postoperative complications,better regulate hormone levels,less damage to olfactory function,better recovery of visual function,and contribute to rapid postoperative recovery.关键词
垂体瘤/神经内镜/经鼻蝶入路垂体瘤切除术/显微镜/垂体功能Key words
Pituitary tumor/Neuroendoscopy/Transsphenoidal pituitary tumor resection/Microscopy/Pituitary function分类
医药卫生引用本文复制引用
饶克成,王淇民,高飞,蔡春雨,解晓燕..神经内镜下经鼻蝶入路垂体瘤切除术对老年垂体瘤患者垂体视觉及嗅觉功能的影响[J].中国实用神经疾病杂志,2026,29(1):43-47,5.基金项目
河南省医学科技攻关计划项目(编号:LHGJ20191472) （编号:LHGJ20191472）
