湖南中医药大学学报2026，Vol.46Issue(1)：82-89,8.DOI:10.3969/j.issn.1674-070X.2026.01.010
针刺颈前五穴对卒中后吞咽障碍患者吞咽功能及血清炎症因子的影响
Effects of acupuncture at five anterior cervical acupoints on swallowing function and serum inflammatory factors in patients with post-stroke dysphagia
摘要
Abstract
Objective To observe the effects of acupuncture at the five anterior cervical acupoints on swallowing function and serum inflammatory factors in patients with post-stroke dysphagia(PSD).Methods A total of 66 PSD patients were divided into five anterior cervical acupoints group and conventional acupuncture group using a random number table method,with 33 cases in each group.During the trial,one case dropped out from the five anterior cervical acupoints group and one from the conventional acupuncture group,resulting in the final inclusion of 32 cases in each group.All patients in both groups were administered basic neurological treatment and basic acupuncture treatment for stroke.On this basis,the five anterior cervical acupoints group received specific acupuncture at the five anterior cervical acupoints,while the conventional acupuncture group received conventional acupuncture treatment.The treatment course was 14 days for both groups.Before and after treatment,the water swallowing test(WST)grade,standardized swallowing assessment(SSA)score,swallowing quality of life(SWAL-QOL)questionnaire score,serum high-sensitivity C-reactive protein(hs-CRP),and serum tumor necrosis factor-α(TNF-α)levels were compared between the two groups.After treatment,the clinical efficacy and occurrence of adverse reactions were compared between the two groups.Results After treatment,the WST grades of both groups decreased compared to before treatment(P<0.01),with an optimized grade distribution,and the five anterior cervical acupoints group was superior to the conventional acupuncture group(P<0.01);the SSA scores of both groups decreased compared to before treatment(P<0.01),and the score of the five anterior cenvical acpoints group was lower than that of the conventional acupuncture group(P<0.05).The SWAL-QOL scores of both groups increased compared to before treatment(P<0.01),and the score of the five anterior cervical acpoints group was higher than that of the conventional acupuncture group(P<0.05);The serum levels of hs-CRP and TNF-α in both groups decreased compared to before treatment(P<0.01),and the levels of the five anterior cervical acupoints group were lower than those in the conventional acupuncture group(P<0.05).The total clinical effective rate of the five anterior cervical acupoints group(93.75%)was significantly higher than that in the conventional acupuncture group(81.25%)(P<0.01),and no adverse events occurred in either group.Conclusion Acupuncture at the five anterior cervical acupo-ints for PSD can effectively improve patients'swallowing function and quality of life,while reducing serum inflammatory factors(hs-CRP and TNF-α)levels.It is safer and more effective than conventional acupuncture treatment.关键词
卒中后吞咽障碍/颈前五穴/针刺/吞咽功能/生活质量/超敏C反应蛋白/肿瘤坏死因子-αKey words
post-stroke dysphagia/five anterior cervical acupoints/acupuncture/swallowing function/quality of life/high-sensitivity C-reactive protein/tumor necrosis factor-α分类
医药卫生引用本文复制引用
高冰洁,顾雪彤,李晓宁..针刺颈前五穴对卒中后吞咽障碍患者吞咽功能及血清炎症因子的影响[J].湖南中医药大学学报,2026,46(1):82-89,8.基金项目
国家中医药管理局高水平中医药重点学科建设项目(14061230010) （14061230010）
黑龙江省自然科学基金项目(PL2024H228) （PL2024H228）
黑龙江省中医药科研项目(GY2022-09). （GY2022-09）
