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基于间充质干细胞治疗自身免疫性肝炎的研究进展

姜有为 王亮 王华

军事医学2025,Vol.49Issue(12):940-948,9.
军事医学2025,Vol.49Issue(12):940-948,9.DOI:10.7644/j.issn.1674-9960.2025.12.010

基于间充质干细胞治疗自身免疫性肝炎的研究进展

Research progress in the treatment of autoimmune hepatitis based on mesenchymal stem cells

姜有为 1王亮 2王华1

作者信息

  • 1. 军事科学院军事医学研究院,北京 100850
  • 2. 32116部队,吉林珲春 133300
  • 折叠

摘要

Abstract

Autoimmune hepatitis(AIH)is an autoimmune liver disease that is getting increasingly prevalent.Notably,mesenchymal stem cells(MSCs)and MSC-based therapeutic strategies promise wide applications in the treatment of AIH.This paper reviews the treatments for AIH based on MSCs by outlining the definition,classification,pathogenesis and its current treatments of AIH,the role and mechanism of MSCs,their extracellular vesicles in treating AIH as well as other therapies based on MSCs.This study is intended to provide references for the development of AIH treatment strategies.

关键词

自身免疫性肝炎/间充质干细胞/外泌体/细胞疗法/非细胞疗法

Key words

autoimmune hepatitis/mesenchymal stem cell/exosome/cell therapy/non-cellular therapy

分类

医药卫生

引用本文复制引用

姜有为,王亮,王华..基于间充质干细胞治疗自身免疫性肝炎的研究进展[J].军事医学,2025,49(12):940-948,9.

军事医学

1674-9960

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