昆明医科大学学报2026，Vol.47Issue(1)：1-15,15.DOI:10.12259/j.issn.2095-610X.S20260101
西南区域高海拔地区世居高原自然人群队列研究进展
Research Progress in the Cohort Study of Native Plateau Populations at High-Altitude in Southwest China
摘要
Abstract
In recent years,the burden of chronic diseases in China has been continuously escalating with significant regional disparities.The local indigenous populations residing in the high-altitude areas of Southwest China have developed unique physiological and genetic traits due to specific geographical and multi-ethnic factors,confronting health challenges such as cardiovascular diseases and metabolic disorders.To conduct a comprehensive analysis the disease distribution patterns and potential exposure factors among this population and to address the data gaps regarding the prevalence of non-communicable diseases(NCDs),risk factors,and related conditions in resource-limited areas with multi-ethnic groups.This study relies on the china multi-ethnic cohort(CMEC)study has established high-altitude natural population cohorts in Lijiang(Yunnan),Aba(Sichuan),and Lhasa(Tibet)to systematically collect baseline data.While health outcomes were monitored through standardized follow-ups to reveal the prevalence rates and their primary risk factors of chronic diseases in high-altitude regions.To explore the impacts of dietary patterns and lifestyle on the metabolic health of plateau populations,discover novel intervention technologies and strategies for chronic diseases,and provide theoretical support for the prevention and control of chronic diseases in Southwest China and even the whole country.关键词
中国西南/高海拔/多民族/慢性病/危险因素Key words
Southwest China/High-altitude/Multi-ethnic/Chronic diseases/Risk factors分类
医药卫生引用本文复制引用
车卓航,钱映,孟琼,张雪辉,扶传文,赵星,殷建忠..西南区域高海拔地区世居高原自然人群队列研究进展[J].昆明医科大学学报,2026,47(1):1-15,15.基金项目
国家重点研发计划"精准医学"重点专项课题(2017YFC0907302) （2017YFC0907302）
国家自然科学基金(82260641,81860597) （82260641,81860597）
云南省基础研究专项计划重点项目(202501AS070132) （202501AS070132）
云南省高校服务重点产业科技项目(博士生服务产业科研创新培育项目,FWCY-BSPY2024079) （博士生服务产业科研创新培育项目,FWCY-BSPY2024079）
云南省赵星专家工作站(202505AF350064) （202505AF350064）
昆明医科大学一流学科特色团队(2024XKTDTS15) （2024XKTDTS15）
