昆明医科大学学报2026，Vol.47Issue(1)：70-78,9.DOI:10.12259/j.issn.2095-610X.S20260109
HIV/AIDS患者血液透析状态下的精神障碍及临床特征调查
Survey on Mental Disorders in HIV/AIDS Patients with End-stage Renal Disease on Hemodialysis
摘要
Abstract
Objective To investigate the incidence and clinical characteristics of anxiety,depression,and sleep disorders in people living with HIV(PLWH)and end-stage renal disease(ESRD)on maintenance hemodialysis(MHD).Methods A cross-sectional study was conducted at Kunming Third People's Hospital from August to December 2024.We consecutively enrolled 51 HIV/AIDS patients with ESRD receiving MHD(HIV-HD group),50 non-HIV ESRD patients receiving MHD(HD group),and randomly selected 102 non-dialysis PLWH at a 1∶2 ratio(HIV group).The hospital anxiety and depression scale(HADS)was used to assess anxiety and depression,and the Pittsburgh sleep quality index(PSQI)was used to evaluate sleep quality.The incidence rates of these conditions were compared among the three groups.Results A total of 203 patients were included.The incidence rates of psychiatric disorders in HIV-HD,HD,and HIV groups were as follows:anxiety(25.5%vs.2 2.0%vs.7.8%),depression(37.3%vs.56.0%vs.17.6%),sleep disorders(86.3%vs.90.0%vs.40.2%),comorbid anxiety and depression(15.7%vs.20.0%vs.3.9%),comorbid anxiety and sleep disorders(23.5%vs.22.0%vs.3.9%),comorbid depression and sleep disorders(33.3%vs.54.0%vs.9.8%),and comorbid anxiety,depression,and sleep disorders(13.7%vs.20.0%vs.2.0%).The incidence of these psychiatric disorders was significantly higher in both the HIV-HD and HD groups compared to the HIV group(P<0.05).Clinical characteristics revealed that the proportions of severe comorbidities(CCI≥5)and hypertension were significantly higher in the HIV-HD and HD groups than in the HIV group,while the prevalence of diabetes was higher in the HD group than in the HIV group(all P<0.05).Conclusion People living with HIV on hemodialysis have a higher incidence of anxiety and depression,and extremely poor sleep quality.关键词
HIV/AIDS/维持性血液透析/焦虑/抑郁/睡眠障碍Key words
HIV/AIDS/Maintenance hemodialysis/Anxiety/Depression/Sleep disorders分类
医药卫生引用本文复制引用
何国念,金永梅,田波,陈寿坤,陆霓虹,刘俊..HIV/AIDS患者血液透析状态下的精神障碍及临床特征调查[J].昆明医科大学学报,2026,47(1):70-78,9.基金项目
国家自然科学基金(82460016) （82460016）
