农业生物技术学报2026，Vol.34Issue(1)：1-12,12.DOI:10.3969/j.issn.1674-7968.2026.01.001
鱼类育性控制技术研究进展
Research Progress on Reproductive Containment Technologies of Fish
摘要
Abstract
Reproductive containment in farmed fish holds significant application potential in improving economic traits,ensuring the industrialization of biological breeding,and protecting intellectual property(IP).Currently,interspecific hybridization and triploid sterility methods have achieved success in the production of sterile broodstock for a limited number of farmed fish species.However,due to technical limitations,these approaches have not yet been widely adopted on a large scale.With the identification of key genes regulating reproduction,the elucidation of gene functions,and advances in genetic engineering techniques,sterile fish can be generated by knocking down or knocking out genes associated with reproduction.However,sterile fish produced directly through gene loss cannot pass on desirable economic traits to the next generation,making it difficult to establish stable families.Therefore,further research is needed on methods to rescue the parental sterility phenotype,such as through exogenous hormone supplementation.Conditional induced sterility and reproductive on-off strategies based on two-line hybridization represent novel approaches to reproductive containment.These techniques enable reproductive containment in fish while ensuring the stable inheritance of parental desirable economic traits.The technical approaches have been preliminarily validated in model fish species,demonstrating promising development prospects.This review summarizes advances in fish reproductive containment technologies,aiming to provide references for breeding economically valuable,ecologically friendly,and IP-protected sterile farmed fish,such as grass carp(Ctenopharyngodon idellus).关键词
养殖鱼类/生物育种/育性控制/基因编辑/生殖调控Key words
Farmed fish/Biological breeding/Reproductive containment/Gene editing/Reproductive regulation分类
农业科技引用本文复制引用
陶彬彬,胡炜..鱼类育性控制技术研究进展[J].农业生物技术学报,2026,34(1):1-12,12.基金项目
科技创新2030-农业生物育种重大项目(2023ZD0405504) （2023ZD0405504）
国家重点研发计划青年科学家项目(2024YFD2402600) （2024YFD2402600）
