山东中医杂志2026，Vol.45Issue(1)：27-31,5.DOI:10.16295/j.cnki.0257-358x.2026.01.006
基于"土壅木郁"探讨胆汁酸-肠道菌群轴对肝内胆汁淤积症的影响
Exploration on Effect of Bile Acid-Intestinal Microbiota Axis on Intrahepatic Cholestasis Based on"Earth Congestion and Wood Stagnation"
摘要
Abstract
Intrahepatic cholestasis is a common liver system disease.The imbalance of the bile acid-intestinal microbiota axis is closely related to the occurrence and development of intrahepatic cholestasis."Earth congestion and wood stagnation"is a pathological process in which the spleen earth is obstructed and counterattacks the liver wood,leading to the stagnation of liver wood.It plays a significant role in the pathogenesis of intrahepatic cholestasis.Intestinal microecological disorder and bile acid metabolism disorder are important manifestations of"earth congestion and wood stagnation".This article explores the relationship among"earth congestion and wood stagnation",bile acid-intestinal microbiota axis imbalance,and intrahepatic cholestasis,and proposes that the bile acid-intestinal microbiota axis can be intervened based on the"earth congestion and wood stagnation"theory to prevent and treat intrahepatic cholestasis,which provides a new idea for the integrated prevention and treatment of intrahepatic cholestasis with traditional Chinese and Western medicine.关键词
土壅木郁/胆汁酸代谢/肠道菌群/肝内胆汁淤积症Key words
earth congestion and wood stagnation/bile acid metabolism/intestinal microflora/intrahe-patic cholestasis分类
医药卫生引用本文复制引用
王文秀,王玉娟,王继衡,于丽丽,段晓东..基于"土壅木郁"探讨胆汁酸-肠道菌群轴对肝内胆汁淤积症的影响[J].山东中医杂志,2026,45(1):27-31,5.基金项目
山东省中医药科技面上项目(编号:2020M098) （编号:2020M098）
济南市卫生健康委员会中医药科技计划专项(编号:2022-中-02) （编号:2022-中-02）
