国际眼科杂志2026，Vol.26Issue(2)：341-346,6.DOI:10.3980/j.issn.1672-5123.2026.2.28
惠州市淡澳地区早产儿眼病的流行病学调查
Epidemiological profile of ocular diseases in preterm infants in Dan'ao area of Huizhou
摘要
Abstract
·AIM:To investigate the prevalence of ocular diseases among premature infants in the Dan'ao area of Huizhou city,and to explore the relevant risk factors for retinopathy of prematurity(ROP),so as to provide a theoretical basis for promoting the implementation of universal ocular disease screening for all premature infants in our city. ·METHODS:A retrospective analysis was performed on the data of premature infants who underwent ocular disease screening in our hospital from June 2023 to December 2024 in the Dan'ao area of Huizhou city.The types and detection rates of ocular diseases in premature infants in this area were statistically analyzed,and the factors influencing the occurrence of ROP were further explored. ·RESULTS:A total of 715 premature infants(1 430 eyes)who received ocular disease screening in our hospital were enrolled in this study,including 428 males and 287 females,with a mean gestational age at birth of 34.59±1.98 wk and a mean birth weight of 2218.64±509.08 g.Among them,178 were twins and 537 were singletons.A total of 70 cases of 10 types of ocular diseases were detected in the 715 preterm infants,with an overall detection rate of 9.79%.Specifically,26 cases(3.64%)were diagnosed with ROP,including 20 cases of stage 1,4 cases of stage 2,and 2 cases of stage 3.Among the ROP patients,73.08%(19/26)had a gestational age≤34 wk at birth,and 69.23%(18/26)had a birth weight<2 000 g.Multivariate Logistic regression analysis revealed that maternal gestational diabetes mellitus(OR:3.493,95%CI:1.292-9.445,P<0.05),gestational hypertension(OR:2.858,95%CI:1.067-7.659,P<0.05),neonatal anemia(OR:3.636,95%CI:1.295-10.212,P<0.05),respiratory distress syndrome(OR:11.128,95%CI:3.369-36.756,P<0.05),and history of oxygen inhalation(OR:5.531,95%CI:1.697-18.031,P<0.05)were all independent risk factors for ROP in premature infants.Additionally,a higher gestational age at birth was identified as a protective factor against ROP(OR:0.557,95%CI:0.389-0.798,P<0.05). ·CONCLUSION:The significance of ocular diseases screening for premature infants lies not only in the detection of ROP but also in the identification of other blinding ocular lesions.Early screening and timely diagnosis and treatment can prevent impairment of visual development in children.关键词
早产儿视网膜病变/早产儿/眼病筛查/危险因素Key words
retinopathy of prematurity/premature infant/ocular disease screening/risk factors引用本文复制引用
宁静静,陈晓凯..惠州市淡澳地区早产儿眼病的流行病学调查[J].国际眼科杂志,2026,26(2):341-346,6.基金项目
2023年度惠州市医疗卫生领域科技计划项目(No.2023CZ010242) 2023 Huizhou Municipal Science and Technology Program Project in the Medical and Health Field(No.2023CZ010242) （No.2023CZ010242）
