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Neuroprotective Kunitz-like peptides identified from the octopus coral Galaxea fascicularis through transcriptomic analysis

Hanbin Chen Hiotong Kam Shirley Weng In Siu Clarence Tsun Ting Wong Jian-Wen Qiu Alex Kwok-Kuen Cheung Gandhi Rádis-Baptista Simon Ming-Yuen Lee

水生生物与安全(英文)2025,Vol.4Issue(3):126-139,14.
水生生物与安全(英文)2025,Vol.4Issue(3):126-139,14.DOI:10.1016/j.watbs.2025.100358

Neuroprotective Kunitz-like peptides identified from the octopus coral Galaxea fascicularis through transcriptomic analysis

Neuroprotective Kunitz-like peptides identified from the octopus coral Galaxea fascicularis through transcriptomic analysis

Hanbin Chen 1Hiotong Kam 2Shirley Weng In Siu 3Clarence Tsun Ting Wong 2Jian-Wen Qiu 4Alex Kwok-Kuen Cheung 5Gandhi Rádis-Baptista 6Simon Ming-Yuen Lee7

作者信息

  • 1. Department of Pharmacology,Joint Laboratory of Guangdong-Hong Kong Universities for Vascular Homeostasis and Diseases,School of Medicine,Southern University of Science and Technology,Shenzhen,China
  • 2. State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences,University of Macau,Macao,China
  • 3. Department of Rehabilitation Sciences,The Hong Kong Polytechnic University,Hong Kong,China
  • 4. Faculty of Applied Sciences,Macao Polytechnic University,Macao,China
  • 5. Department of Applied Biology and Chemical Technology,The Hong Kong Polytechnic University,Hong Kong,China
  • 6. Department of Biology,Hong Kong Baptist University,Hong Kong,China
  • 7. Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou),Guangzhou,China
  • 折叠

摘要

关键词

Kunitz-type peptides/Neuroprotective effect/Potassium ion channel/Nrf2 signaling pathway

Key words

Kunitz-type peptides/Neuroprotective effect/Potassium ion channel/Nrf2 signaling pathway

引用本文复制引用

Hanbin Chen,Hiotong Kam,Shirley Weng In Siu,Clarence Tsun Ting Wong,Jian-Wen Qiu,Alex Kwok-Kuen Cheung,Gandhi Rádis-Baptista,Simon Ming-Yuen Lee..Neuroprotective Kunitz-like peptides identified from the octopus coral Galaxea fascicularis through transcriptomic analysis[J].水生生物与安全(英文),2025,4(3):126-139,14.

基金项目

This work was supported by the China Postdoctoral Science Foun-dation under Grant Number 2023M731524,University of Macau and funded by The Science and Technology Development Fund(FDTC)of Macau SAR(File no.0058/2019/A1 and 0016/2019/AKP),University of Macau(MYRG2019-00105-ICMS)and The Hong Kong Polytechnic Uni-versity(Project ID.P0006304).The Environmental and Conservation Fund of Hong Kong(grant no.34/2019),and Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong laboratory(Guangzhou)(grant nos.GMl2019ZD0404,SMSEGl20SC02).This work was performed in part at the high perfor-mance computing cluster(HPCC)which is supported by the Information and Communication Technology office(ICTO)of the University of Macau. (FDTC)

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