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基于Watson关怀理论的干预方案在接受免疫检查点抑制剂治疗的肺癌患者中的应用效果

顾佳华 任一美 龚建红 陆佳莹 卞银花

实用心脑肺血管病杂志2026,Vol.34Issue(3):20-24,5.
实用心脑肺血管病杂志2026,Vol.34Issue(3):20-24,5.DOI:10.12114/j.issn.1008-5971.2026.00.070

基于Watson关怀理论的干预方案在接受免疫检查点抑制剂治疗的肺癌患者中的应用效果

Application Effect of Intervention Program Based on Watson Theory of Care in Lung Cancer Patients Undergoing Immune Checkpoint Inhibitors Therapy

顾佳华 1任一美 1龚建红 1陆佳莹 1卞银花1

作者信息

  • 1. 226200 江苏省启东市人民医院 启东肝癌防治研究所 南通大学附属启东医院肿瘤科
  • 折叠

摘要

Abstract

Objective To investigate the application effect of intervention program based on Watson theory of care in lung cancer patients undergoing immune checkpoint inhibitors(ICIs)therapy.Methods A total of 74 lung cancer patients who received ICIs treatment and were admitted to the Oncology Department,Qidong People's Hospital from January to April 2025 were selected as the study subjects.Based on the intervention method,patients were divided into the Watson group and the regular group,with 37 cases in each group.Patients in the regular group received conventional intervention program,while those in the Watson group received intervention program based on Watson theory of care,for a total intervention period of 6 months.The scores of Revised Piper Fatigue Scale(PFS-R),Chinese version of Multidimensional Fatigue Symptom Inventory-Short Form(MFSI-SF),Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA),and Chinese version of Cancer Rehabilitation Evaluation System-Short Form(CARES-SF)before intervention and at 3 and 6 months after intervention were compared between the two groups.Results The PFS-R and Chinese version of MFSI-SF scores of the Watson group were lower than those of the regular group at 3 and 6 months after intervention(P<0.05).In the regular group and Watson group,the PFS-R and Chinese version of MFSI-SF scores at 3 and 6 months after intervention were higher than those before intervention,and the PFS-R and Chinese version of MFSI-SF scores at 6 months after intervention were lower than those at 3 months after intervention,respectively(P<0.05).The HAMD and HAMA scores of the Watson group were lower than those of the regular group at 3 and 6 months after intervention(P<0.05).In the regular group and Watson group,the HAMD and HAMA scores at 3 and 6 months after intervention were lower than those before intervention,and the HAMD and HAMA scores at 6 months after intervention were lower than those at 3 months after intervention,respectively(P<0.05).The scores of each dimension and the total score of the Chinese version of CARES-SF at 3 and 6 months after intervention in the Watson group were lower than those in the regular group(P<0.05).In the regular group and Watson group,the scores of each dimension and the total score of the Chinese version of CARES-SF at 3 and 6 months after intervention were lower than those before intervention,the scores of each dimension and the total score of the Chinese version of CARES-SF at 6 months after intervention were lower than those at 3 months after intervention,respectively(P<0.05).Conclusion The intervention program based on Watson theory of care can effectively alleviate cancer-related fatigue,depression,and anxiety in lung cancer patients undergoing ICIs treatment,thereby improving their quality of life.

关键词

肺肿瘤/免疫检查点抑制剂/Watson关怀理论

Key words

Lung neoplasms/Immune checkpoint inhibitors/Watson theory of care

分类

医药卫生

引用本文复制引用

顾佳华,任一美,龚建红,陆佳莹,卞银花..基于Watson关怀理论的干预方案在接受免疫检查点抑制剂治疗的肺癌患者中的应用效果[J].实用心脑肺血管病杂志,2026,34(3):20-24,5.

基金项目

南通市卫生健康委员会科研课题(MSZ2024109) (MSZ2024109)

实用心脑肺血管病杂志

1008-5971

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