饲料工业2026,Vol.47Issue(2):48-55,8.DOI:10.13302/j.cnki.fi.2026.02.007
低能量饲粮中添加二氯乙酸钾对肉鸡生长性能、血液生化指标与肠道功能的影响
Effects of Adding Potassium Dichloroacetate in Low-Energy Diets on Growth Performance,Blood Biochemical Indexes and Intestinal Function of Broilers
摘要
Abstract
The experiment aimed to investigate the effect of supplementation of Potassium dichloroacetate(DCA-K)in low-energy diets on broilers.Two hundred and seventy 1-day-old Cobb 500 broilers were randomly divided into three groups(6 repli-cates per group,15 broilers per replicate),which were control group(CON group,energy level of 12.85 MJ/kg),low-energy group(LME group,energy level of 12.43 MJ/kg),and the low-energy+potassium dichloroacetate group(LME+DCA-K group,energy level of 12.43 MJ/kg,with a DCA-K addition of 0.1%).The experimental period was 35 days.The results showed that the body weight and average daily gain were significantly lower and the feed-to-weight ratio was significantly higher in the LME group compared with the CON group(P<0.05).Calcium(Ca)content in plasma was significantly lower in broilers in the LME group compared to the CON group(P<0.05),and supplementation with DCA-K on the basis of a low-energy diet significantly increased plasma ALT concentration and HDL content and significantly decreased plasma TG and LDL content(P<0.05).The LME group significantly increased duodenal lipase and jejunal trypsin activities in broilers compared to the CON group(P<0.05).The LME+DCA-K group significantly increased duodenal and jejunal trypsin activity and jejunal lipase activity and dialed back duodenal lipase activity compared to the LME group(P<0.05).Compared with the CON group,the LME group significantly down-regulated the mRNA levels of broiler jejunal Mucin-2,SLC1A1,SGLT-1,KCNJ13,LXRα,and FABP4.The LME+DCA-K group significantly up-regulated the mRNA levels of these genes,as well as significantly up-regulated the mRNA levels of SLC7A7(P<0.05).In conclusion,the addition of 0.1%DCA-K to low-energy diets can improve blood biochemical indexes and intestinal barrier function of broilers,as well as enhance intestinal absorption of amino acids and lipids.关键词
二氯乙酸钾/低能量饲粮/肉鸡/生长性能/肠道功能Key words
potassium dichloroacetate/low-energy diet/broilers/growth performance/intestinal function分类
农业科技引用本文复制引用
刘佳乐,石文慧,柳苗苗,吴梦郡,孙香雪,易丹,郭双双,查宇,李鹏..低能量饲粮中添加二氯乙酸钾对肉鸡生长性能、血液生化指标与肠道功能的影响[J].饲料工业,2026,47(2):48-55,8.基金项目
湖北省自然科学基金-青年基金[2023AFB354] ()
武汉市知识创新专项曙光计划[2023020201020461] ()